TY  - JOUR
AU  - Zamora-Ros, Raul
AU  - Cayssials, Valerie
AU  - Jenab, Mazda
AU  - Rothwell, Joseph A
AU  - Fedirko, Veronika
AU  - Aleksandrova, Krasimira
AU  - Tjønneland, Anne
AU  - Kyrø, Cecilie
AU  - Overvad, Kim
AU  - Boutron-Ruault, Marie-Christine
AU  - Carbonnel, Franck
AU  - Mahamat-Saleh, Yahya
AU  - Kaaks, Rudolf
AU  - Kühn, Tilman
AU  - Boeing, Heiner
AU  - Trichopoulou, Antonia
AU  - Valanou, Elissavet
AU  - Vasilopoulou, Effie
AU  - Masala, Giovanna
AU  - Pala, Valeria
AU  - Panico, Salvatore
AU  - Tumino, Rosario
AU  - Ricceri, Fulvio
AU  - Weiderpass, Elisabete
AU  - Lukic, Marko
AU  - Sandanger, Torkjel M
AU  - Lasheras, Cristina
AU  - Agudo, Antonio
AU  - Sánchez, Maria-Jose
AU  - Amiano, Pilar
AU  - Navarro, Carmen
AU  - Ardanaz, Eva
AU  - Sonestedt, Emily
AU  - Ohlsson, Bodil
AU  - Nilsson, Lena Maria
AU  - Rutegård, Martin
AU  - Bueno-de-Mesquita, Bas
AU  - Peeters, Petra H
AU  - Khaw, Kay-Thee
AU  - Wareham, Nicholas J
AU  - Bradbury, Kathryn
AU  - Freisling, Heinz
AU  - Romieu, Isabelle
AU  - Cross, Amanda J
AU  - Vineis, Paolo
AU  - Scalbert, Augustin
TI  - Dietary intake of total polyphenol and polyphenol classes and the risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.
JO  - European journal of epidemiology
VL  - 33
IS  - 11
SN  - 1573-7284
CY  - Dordrecht [u.a.]
PB  - Springer Science + Business Media B.V.
M1  - DKFZ-2018-01780
SP  - 1063 - 1075
PY  - 2018
AB  - Polyphenols may play a chemopreventive role in colorectal cancer (CRC); however, epidemiological evidence supporting a role for intake of individual polyphenol classes, other than flavonoids is insufficient. We evaluated the association between dietary intakes of total and individual classes and subclasses of polyphenols and CRC risk and its main subsites, colon and rectum, within the European Prospective Investigation into Cancer and Nutrition (EPIC) study. The cohort included 476,160 men and women from 10 European countries. During a mean follow-up of 14 years, there were 5991 incident CRC cases, of which 3897 were in the colon and 2094 were in the rectum. Polyphenol intake was estimated using validated centre/country specific dietary questionnaires and the Phenol-Explorer database. In multivariable-adjusted Cox regression models, a doubling in total dietary polyphenol intake was not associated with CRC risk in women (HRlog2 = 1.06, 95
LB  - PUB:(DE-HGF)16
C6  - pmid:29761424
DO  - DOI:10.1007/s10654-018-0408-6
UR  - https://inrepo02.dkfz.de/record/141260
ER  -