%0 Journal Article %A Zimmer, Philipp %A Bloch, Wilhelm %A Schenk, Alexander %A Oberste, Max %A Riedel, Stefan %A Kool, Jan %A Langdon, Dawn %A Dalgas, Ulrik %A Kesselring, Jürg %A Bansi, Jens %T High-intensity interval exercise improves cognitive performance and reduces matrix metalloproteinases-2 serum levels in persons with multiple sclerosis: A randomized controlled trial. %J Multiple sclerosis journal %V 24 %N 12 %@ 1477-0970 %C London %I Sage %M DKFZ-2018-01781 %P 1635 - 1644 %D 2018 %X Aerobic exercise can improve cognitive performance in healthy elderly people.The aim of this study was to investigate the influence of a 3-week high-intensity aerobic exercise programme (high-intensity training group (HIT)) on cognitive performance in persons with multiple sclerosis (MS) compared with a standard exercise programme (control training (CT)).A total of 60 persons with MS (Expanded Disability Status Scale (EDSS): 1.0-6.5) were randomized to a HIT group (3×/week for 20 minutes, including five 3-minute exercise intervals at 80 %F PUB:(DE-HGF)16 %9 Journal Article %$ pmid:28825348 %R 10.1177/1352458517728342 %U https://inrepo02.dkfz.de/record/141261