TY - JOUR
AU - Koerber, Stefan A
AU - Will, Leon
AU - Kratochwil, Clemens
AU - Haefner, Matthias F
AU - Rathke, Henrik
AU - Kremer, Christophe
AU - Merkle, Jonas
AU - Herfarth, Klaus
AU - Kopka, Klaus
AU - Choyke, Peter L
AU - Holland-Letz, Tim
AU - Haberkorn, Uwe
AU - Debus, Juergen
AU - Giesel, Frederik
TI - 68Ga-PSMA-11 PET/CT in Primary and Recurrent Prostate Carcinoma: Implications for Radiotherapeutic Management in 121 Patients.
JO - Journal of nuclear medicine
VL - 60
IS - 2
SN - 2159-662X
CY - New York, NY
PB - Soc.
M1 - DKFZ-2018-01906
SP - 234-240
PY - 2019
N1 - vol. 60 no. 2 234-240
AB - The present study analyzed the impact of Gallium-68 (68Ga)-labeled prostate-specific membrane antigen-HBED-CC (68Ga-PSMA-11) positron-emission tomography (PET)/computed tomography (CT) on radiotherapeutic management in a large cohort of men with primary or recurrent disease. Methods: This study investigated 121 men with carcinoma of the prostate who underwent 68Ga-PSMA-11 PET/CT as well as conventional imaging. 50 patients were treatment naive, 11 had persistent prostate-specific antigen (PSA) soon after surgery and 60 presented with recurrent PSA following definitive therapy. Changes in TNM classification of malignant tumors (TNM) stage and radiotherapeutic management after 68Ga-PSMA-11 imaging were compared to results achieved with conventional imaging. Results: In total, a change in TNM stage and radiotherapeutic management was observed for 49 patients (40.5
LB - PUB:(DE-HGF)16
C6 - pmid:29976697
DO - DOI:10.2967/jnumed.118.211086
UR - https://inrepo02.dkfz.de/record/141400
ER -