%0 Journal Article
%A Jaskulski, Stefanie
%A Jung, Audrey Ying-Chee
%A Behrens, Sabine
%A Johnson, Theron Scot
%A Kaaks, Rudolf
%A Thöne, Kathrin
%A Flesch-Janys, Dieter
%A Sookthai, Disorn
%A Chang-Claude, Jenny
%T Circulating enterolactone concentrations and prognosis of postmenopausal breast cancer: assessment of mediation by inflammatory markers.
%J International journal of cancer
%V 143
%N 11
%@ 0020-7136
%C Bognor Regis
%I Wiley-Liss
%M DKFZ-2018-01926
%P 2698 - 2708
%D 2018
%X Higher lignan exposure has been associated with lower all-cause mortality (ACM) and breast cancer-specific mortality (BCSM) for postmenopausal breast cancer patients. However, the biological mechanisms underpinning these associations are still unclear. We investigated for the first time whether and to what extent the association between enterolactone (ENL), the major lignan metabolite, and postmenopausal breast cancer prognosis is mediated by inflammatory biomarkers. Circulating concentrations of ENL and inflammatory markers were measured in a population-based prospective cohort of 1,743 breast cancer patients recruited between 2002 and 2005 and followed-up until 2009. Hazard ratios (HR) and 95
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:29974464
%R 10.1002/ijc.31647
%U https://inrepo02.dkfz.de/record/141420