TY  - JOUR
AU  - Jaskulski, Stefanie
AU  - Jung, Audrey Ying-Chee
AU  - Behrens, Sabine
AU  - Johnson, Theron Scot
AU  - Kaaks, Rudolf
AU  - Thöne, Kathrin
AU  - Flesch-Janys, Dieter
AU  - Sookthai, Disorn
AU  - Chang-Claude, Jenny
TI  - Circulating enterolactone concentrations and prognosis of postmenopausal breast cancer: assessment of mediation by inflammatory markers.
JO  - International journal of cancer
VL  - 143
IS  - 11
SN  - 0020-7136
CY  - Bognor Regis
PB  - Wiley-Liss
M1  - DKFZ-2018-01926
SP  - 2698 - 2708
PY  - 2018
AB  - Higher lignan exposure has been associated with lower all-cause mortality (ACM) and breast cancer-specific mortality (BCSM) for postmenopausal breast cancer patients. However, the biological mechanisms underpinning these associations are still unclear. We investigated for the first time whether and to what extent the association between enterolactone (ENL), the major lignan metabolite, and postmenopausal breast cancer prognosis is mediated by inflammatory biomarkers. Circulating concentrations of ENL and inflammatory markers were measured in a population-based prospective cohort of 1,743 breast cancer patients recruited between 2002 and 2005 and followed-up until 2009. Hazard ratios (HR) and 95
LB  - PUB:(DE-HGF)16
C6  - pmid:29974464
DO  - DOI:10.1002/ijc.31647
UR  - https://inrepo02.dkfz.de/record/141420
ER  -