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@ARTICLE{Olsson:141688,
      author       = {A. Olsson and K. Togawa and J. Schüz and C. Le Cornet$^*$
                      and B. Fervers and S. Oksbjerg Dalton and E. Pukkala and M.
                      F. Maria Feychting and N. E. Skakkebæk and J. Hansen},
      title        = {{P}arental occupational exposure to solvents and heavy
                      metals and risk of developing testicular germ cell tumors in
                      sons ({NORD}-{TEST} {D}enmark).},
      journal      = {Scandinavian journal of work, environment $\&$ health},
      volume       = {44},
      number       = {6},
      issn         = {1795-990X},
      address      = {Helsinki},
      publisher    = {Finnish Inst. of Occupational Health},
      reportid     = {DKFZ-2018-01959},
      pages        = {658 - 669},
      year         = {2018},
      abstract     = {Objective The present study aims to assess if parental
                      occupational exposure to solvents or heavy metals is
                      associated with risk of testicular germ cell tumors (TGCT)
                      in sons in Denmark. Methods The NORD-TEST Denmark included
                      3421 cases diagnosed with TGCT at ages 14-49 years in
                      Denmark between 1981 and 2014. Controls (N=14 024) selected
                      from the central population registry were matched to cases
                      on birth year. The Danish Supplementary Pension Fund
                      provided parental occupational information. A job-exposure
                      matrix was used to assign exposures, and conditional
                      logistic regression models were used to estimate odds ratios
                      (OR) and $95\%$ confidence intervals (CI). Results The
                      overall analyses showed no significant associations except
                      for paternal exposure to a sub-group of 'heavy metal(s) and
                      solvent(s)' (OR 1.50, $95\%$ CI 1.01-2.24). Most fathers in
                      this category had worked in wood related jobs and were
                      assigned exposure to chromium VI and toluene. Other
                      sub-group analyses suggested that maternal exposure to
                      aromatic hydrocarbon were associated with TGCT risk, in sons
                      born in 1970-1979, and to heavy metals (chromium, iron and
                      nickel) in sons born in 1980-1998. Conclusion NORD-TEST
                      Denmark provides no strong support for an association
                      between parental exposures to solvents or heavy metals and
                      TGCT in sons, and only weak support for an association
                      between paternal exposure to chromium and toluene and TGCT
                      risk in sons.},
      cin          = {C020},
      ddc          = {610},
      cid          = {I:(DE-He78)C020-20160331},
      pnm          = {313 - Cancer risk factors and prevention (POF3-313)},
      pid          = {G:(DE-HGF)POF3-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:29877553},
      doi          = {10.5271/sjweh.3732},
      url          = {https://inrepo02.dkfz.de/record/141688},
}