001     141765
005     20240229112526.0
024 7 _ |a 10.1016/j.canep.2018.10.006
|2 doi
024 7 _ |a pmid:30445228
|2 pmid
024 7 _ |a 1877-7821
|2 ISSN
024 7 _ |a 1877-783X
|2 ISSN
024 7 _ |a altmetric:52563605
|2 altmetric
037 _ _ |a DKFZ-2018-02034
041 _ _ |a eng
082 _ _ |a 610
100 1 _ |a Brenner, Darren R
|b 0
245 _ _ |a Alcohol consumption and lung cancer risk: A pooled analysis from the International Lung Cancer Consortium and the SYNERGY study.
260 _ _ |a Amsterdam [u.a.]
|c 2019
|b Elsevier
336 7 _ |a article
|2 DRIVER
336 7 _ |a Output Types/Journal article
|2 DataCite
336 7 _ |a Journal Article
|b journal
|m journal
|0 PUB:(DE-HGF)16
|s 1555405791_10187
|2 PUB:(DE-HGF)
336 7 _ |a ARTICLE
|2 BibTeX
336 7 _ |a JOURNAL_ARTICLE
|2 ORCID
336 7 _ |a Journal Article
|0 0
|2 EndNote
520 _ _ |a There is inadequate evidence to determine whether there is an effect of alcohol consumption on lung cancer risk. We conducted a pooled analysis of data from the International Lung Cancer Consortium and the SYNERGY study to investigate this possible association by type of beverage with adjustment for other potential confounders.Twenty one case-control studies and one cohort study with alcohol-intake data obtained from questionnaires were included in this pooled analysis (19,149 cases and 362,340 controls). Adjusted odds ratios (OR) or hazard ratios (HR) with corresponding 95% confidence intervals (CI) were estimated for each measure of alcohol consumption. Effect estimates were combined using random or fixed-effects models where appropriate. Associations were examined for overall lung cancer and by histological type.We observed an inverse association between overall risk of lung cancer and consumption of alcoholic beverages compared to non-drinkers, but the association was not monotonic. The lowest risk was observed for persons who consumed 10-19.9 g/day ethanol (OR vs. non-drinkers = 0.78; 95% CI: 0.67, 0.91), where 1 drink is approximately 12-15 g. This J-shaped association was most prominent for squamous cell carcinoma (SCC). The association with all lung cancer varied little by type of alcoholic beverage, but there were notable differences for SCC. We observed an association with beer intake (OR for ≥20 g/day vs nondrinker = 1.42; 95% CI: 1.06, 1.90).Whether the non-monotonic associations we observed or the positive association between beer drinking and squamous cell carcinoma reflect real effects await future analyses and insights about possible biological mechanisms.
536 _ _ |a 313 - Cancer risk factors and prevention (POF3-313)
|0 G:(DE-HGF)POF3-313
|c POF3-313
|f POF III
|x 0
588 _ _ |a Dataset connected to CrossRef, PubMed,
700 1 _ |a Fehringer, Gord
|b 1
700 1 _ |a Zhang, Zuo-Feng
|b 2
700 1 _ |a Lee, Yuan-Chin Amy
|b 3
700 1 _ |a Meyers, Travis
|b 4
700 1 _ |a Matsuo, Keitaro
|b 5
700 1 _ |a Ito, Hidemi
|b 6
700 1 _ |a Vineis, Paolo
|b 7
700 1 _ |a Stucker, Isabelle
|b 8
700 1 _ |a Boffetta, Paolo
|b 9
700 1 _ |a Brennan, Paul
|b 10
700 1 _ |a Christiani, David C
|b 11
700 1 _ |a Diao, Nancy
|b 12
700 1 _ |a Hong, Yun-Chul
|b 13
700 1 _ |a Landi, Maria T
|b 14
700 1 _ |a Morgenstern, Hal
|b 15
700 1 _ |a Schwartz, Ann G
|b 16
700 1 _ |a Rennert, Gad
|b 17
700 1 _ |a Saliba, Walid
|b 18
700 1 _ |a McLaughlin, John R
|b 19
700 1 _ |a Harris, Curtis C
|b 20
700 1 _ |a Orlow, Irene
|b 21
700 1 _ |a Barros Dios, Juan M
|b 22
700 1 _ |a Ruano Raviña, Alberto
|b 23
700 1 _ |a Siemiatycki, Jack
|b 24
700 1 _ |a Koushik, Anita
|b 25
700 1 _ |a Cote, Michele
|b 26
700 1 _ |a Lazarus, Philip
|b 27
700 1 _ |a Fernandez-Tardon, Guillermo
|b 28
700 1 _ |a Tardon, Adonina
|b 29
700 1 _ |a Le Marchand, Loïc
|b 30
700 1 _ |a Brenner, Hermann
|0 P:(DE-He78)90d5535ff896e70eed81f4a4f6f22ae2
|b 31
|u dkfz
700 1 _ |a Saum, Kai-Uwe
|0 P:(DE-He78)97343bbd9545a4b87574e74329dabfd1
|b 32
|u dkfz
700 1 _ |a Duell, Eric J
|b 33
700 1 _ |a Andrew, Angeline S
|b 34
700 1 _ |a Consonni, Dario
|b 35
700 1 _ |a Olsson, Ann
|b 36
700 1 _ |a Hung, Rayjean J
|b 37
700 1 _ |a Straif, Kurt
|b 38
773 _ _ |a 10.1016/j.canep.2018.10.006
|g Vol. 58, p. 25 - 32
|0 PERI:(DE-600)2498032-8
|p 25 - 32
|t Cancer epidemiology
|v 58
|y 2019
|x 1877-7821
909 C O |p VDB
|o oai:inrepo02.dkfz.de:141765
910 1 _ |a Deutsches Krebsforschungszentrum
|0 I:(DE-588b)2036810-0
|k DKFZ
|b 31
|6 P:(DE-He78)90d5535ff896e70eed81f4a4f6f22ae2
910 1 _ |a Deutsches Krebsforschungszentrum
|0 I:(DE-588b)2036810-0
|k DKFZ
|b 32
|6 P:(DE-He78)97343bbd9545a4b87574e74329dabfd1
913 1 _ |a DE-HGF
|l Krebsforschung
|1 G:(DE-HGF)POF3-310
|0 G:(DE-HGF)POF3-313
|2 G:(DE-HGF)POF3-300
|v Cancer risk factors and prevention
|x 0
|4 G:(DE-HGF)POF
|3 G:(DE-HGF)POF3
|b Gesundheit
914 1 _ |y 2019
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0300
|2 StatID
|b Medline
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0310
|2 StatID
|b NCBI Molecular Biology Database
915 _ _ |a JCR
|0 StatID:(DE-HGF)0100
|2 StatID
|b CANCER EPIDEMIOL : 2017
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0200
|2 StatID
|b SCOPUS
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0600
|2 StatID
|b Ebsco Academic Search
915 _ _ |a Peer Review
|0 StatID:(DE-HGF)0030
|2 StatID
|b ASC
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0199
|2 StatID
|b Clarivate Analytics Master Journal List
915 _ _ |a WoS
|0 StatID:(DE-HGF)0111
|2 StatID
|b Science Citation Index Expanded
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0150
|2 StatID
|b Web of Science Core Collection
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1110
|2 StatID
|b Current Contents - Clinical Medicine
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1050
|2 StatID
|b BIOSIS Previews
915 _ _ |a IF < 5
|0 StatID:(DE-HGF)9900
|2 StatID
920 1 _ |0 I:(DE-He78)C070-20160331
|k C070
|l Klinische Epidemiologie und Alternsforschung
|x 0
920 1 _ |0 I:(DE-He78)C120-20160331
|k C120
|l Präventive Onkologie
|x 1
920 1 _ |0 I:(DE-He78)L101-20160331
|k L101
|l DKTK Heidelberg
|x 2
980 _ _ |a journal
980 _ _ |a VDB
980 _ _ |a I:(DE-He78)C070-20160331
980 _ _ |a I:(DE-He78)C120-20160331
980 _ _ |a I:(DE-He78)L101-20160331
980 _ _ |a UNRESTRICTED


LibraryCollectionCLSMajorCLSMinorLanguageAuthor
Marc 21