TY  - JOUR
AU  - Travis, Ruth C
AU  - Perez-Cornago, Aurora
AU  - Appleby, Paul N
AU  - Albanes, Demetrius
AU  - Joshu, Corinne E
AU  - Lutsey, Pamela L
AU  - Mondul, Alison M
AU  - Platz, Elizabeth A
AU  - Weinstein, Stephanie J
AU  - Layne, Tracy M
AU  - Helzlsouer, Kathy J
AU  - Visvanathan, Kala
AU  - Palli, Domenico
AU  - Peeters, Petra H
AU  - Bueno-de-Mesquita, Bas
AU  - Trichopoulou, Antonia
AU  - Gunter, Marc J
AU  - Tsilidis, Konstantinos K
AU  - Sanchez, Maria-Jose
AU  - Olsen, Anja
AU  - Brenner, Hermann
AU  - Schöttker, Ben
AU  - Perna, Laura
AU  - Holleczek, Bernd
AU  - Knekt, Paul
AU  - Rissanen, Harri
AU  - Yeap, Bu B
AU  - Flicker, Leon
AU  - Almeida, Osvaldo P
AU  - Wong, Yuen Yee Elizabeth
AU  - Chan, June M
AU  - Giovannucci, Edward L
AU  - Stampfer, Meir J
AU  - Ursin, Giske
AU  - Gislefoss, Randi E
AU  - Bjørge, Tone
AU  - Meyer, Haakon E
AU  - Blomhoff, Rune
AU  - Tsugane, Shoichiro
AU  - Sawada, Norie
AU  - English, Dallas R
AU  - Eyles, Darryl W
AU  - Heath, Alicia K
AU  - Williamson, Elizabeth J
AU  - Manjer, Jonas
AU  - Malm, Johan
AU  - Almquist, Martin
AU  - Le Marchand, Loic
AU  - Haiman, Christopher A
AU  - Wilkens, Lynne R
AU  - Schenk, Jeannette M
AU  - Tangen, Cathy M
AU  - Black, Amanda
AU  - Cook, Michael B
AU  - Huang, Wen-Yi
AU  - Ziegler, Regina G
AU  - Martin, Richard M
AU  - Hamdy, Freddie C
AU  - Donovan, Jenny L
AU  - Neal, David E
AU  - Touvier, Mathilde
AU  - Hercberg, Serge
AU  - Galan, Pilar
AU  - Deschasaux, Mélanie
AU  - Key, Timothy J
AU  - Allen, Naomi E
TI  - A collaborative analysis of individual participant data from 19 prospective studies assesses circulating vitamin D and prostate cancer risk.
JO  - Cancer research
VL  - 79
IS  - 1
SN  - 1538-7445
CY  - Philadelphia, Pa.
PB  - AACR
M1  - DKFZ-2018-02044
SP  - 274-285
PY  - 2019
AB  - Previous prospective studies assessing the relationship between circulating concentrations of vitamin D and prostate cancer risk have shown inconclusive results, particularly for risk of aggressive disease. In this study, we examine the association between pre-diagnostic concentrations of 25-hydroxyvitamin D (25(OH)D) and 1,25(OH)2D and the risk of prostate cancer overall and by tumor characteristics. Principal investigators of 19 prospective studies provided individual participant data on circulating 25(OH)D and 1,25(OH)2D for up to 13,462 men with incident prostate cancer and 20,261 control participants. Odds ratios (OR) for prostate cancer by study-specific fifths of season-standardized vitamin D concentration were estimated using multivariable-adjusted conditional logistic regression. 25(OH)D concentration was positively associated with risk for total prostate cancer (multivariable-adjusted OR comparing highest versus lowest study-specific fifth was 1.22, 95
LB  - PUB:(DE-HGF)16
C6  - pmid:30425058
DO  - DOI:10.1158/0008-5472.CAN-18-2318
UR  - https://inrepo02.dkfz.de/record/141775
ER  -