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000141817 1001_ $$aCostas, Laura$$b0
000141817 245__ $$aReproductive factors, exogenous hormone use and risk of B-cell non-Hodgkin lymphoma in a cohort of women from the European Prospective Investigation into Cancer and Nutrition.
000141817 260__ $$aOxford$$bOxford Univ. Press$$c2019
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000141817 520__ $$aThe role of hormonal factors in lymphoid neoplasms etiology remains unclear. Previous studies have yielded conflicting results, been underpowered to assess many lymphoma subtypes, or lacked detailed information on relevant exposures. Within the European Prospective Investigation into Cancer and Nutrition cohort, we analyzed comprehensive data collected at baseline (1992-2000) on reproductive factors and exogenous hormone use among 343,458 women, including 1,427 incident B-cell non-Hodgkin lymphomas (NHL) and its major subtypes identified after a mean follow-up of 14 years (through 2015). We estimated hazard ratios and 95% confidence intervals using multivariable proportional hazards modeling. Overall, we observed no statistically significant associations between parity, age at first birth, breastfeeding, oral contraceptive use or ever use of postmenopausal hormone therapy and risk of B-cell NHL or its subtypes. Women who had a surgical menopause had a 51% higher risk of B-cell NHL (based on 67 cases) compared with natural menopause (hazard ratio=1.51, 95% confidence interval=1.17, 1.94). Given that this result may be due to chance, our results provide little support for the hypothesis that sex hormones play a role in lymphomagenesis.
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000141817 7001_ $$aLujan-Barroso, Leila$$b1
000141817 7001_ $$aBenavente, Yolanda$$b2
000141817 7001_ $$aAllen, Naomi E$$b3
000141817 7001_ $$aAmiano, Pilar$$b4
000141817 7001_ $$aArdanaz, Eva$$b5
000141817 7001_ $$aBesson, Caroline$$b6
000141817 7001_ $$aBoeing, Heiner$$b7
000141817 7001_ $$aBueno-de-Mesquita, Bas$$b8
000141817 7001_ $$aCervenka, Iris$$b9
000141817 7001_ $$0P:(DE-HGF)0$$aFortner, R Enée T$$b10
000141817 7001_ $$aFournier, Agnès$$b11
000141817 7001_ $$aGunter, Marc$$b12
000141817 7001_ $$aHarlid, Sophia$$b13
000141817 7001_ $$aHuerta, José María$$b14
000141817 7001_ $$aJerkeman, Mats$$b15
000141817 7001_ $$aJirström, Karin$$b16
000141817 7001_ $$0P:(DE-He78)4b2dc91c9d1ac33a1c0e0777d0c1697a$$aKaaks, Rudolf$$b17$$udkfz
000141817 7001_ $$aKarakatsani, Anna$$b18
000141817 7001_ $$aKhaw, Kay-Tee$$b19
000141817 7001_ $$aKotanidou, Anastasia$$b20
000141817 7001_ $$aLund, Eiliv$$b21
000141817 7001_ $$aMasala, Giovanna$$b22
000141817 7001_ $$aMattiello, Amalia$$b23
000141817 7001_ $$aMelin, Beatrice$$b24
000141817 7001_ $$aMenéndez, Virginia$$b25
000141817 7001_ $$aMurphy, Neil$$b26
000141817 7001_ $$aNieters, Alexandra$$b27
000141817 7001_ $$aOvervad, Kim$$b28
000141817 7001_ $$aRiboli, Elio$$b29
000141817 7001_ $$aSacerdote, Carlotta$$b30
000141817 7001_ $$aSánchez, Maria-Jose$$b31
000141817 7001_ $$aSchmidt, Julie A$$b32
000141817 7001_ $$aSieri, Sabina$$b33
000141817 7001_ $$aTjønneland, Anne$$b34
000141817 7001_ $$aTrichopoulou, Antonia$$b35
000141817 7001_ $$aTumino, Rosario$$b36
000141817 7001_ $$aVermeulen, Roel$$b37
000141817 7001_ $$aWeiderpass, Elisabete$$b38
000141817 7001_ $$ade Sanjosé, Silvia$$b39
000141817 7001_ $$aAgudo, Antonio$$b40
000141817 7001_ $$aCasabonne, Delphine$$b41
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