001     141872
005     20240229121827.0
024 7 _ |a 10.1016/j.ijcard.2018.09.035
|2 doi
024 7 _ |a pmid:30217425
|2 pmid
024 7 _ |a 0167-5273
|2 ISSN
024 7 _ |a 1874-1754
|2 ISSN
024 7 _ |a altmetric:48483642
|2 altmetric
037 _ _ |a DKFZ-2018-02129
041 _ _ |a eng
082 _ _ |a 610
100 1 _ |a Ittermann, Till
|b 0
245 _ _ |a Changes in fat mass and fat-free-mass are associated with incident hypertension in four population-based studies from Germany.
260 _ _ |a Amsterdam [u.a.]
|c 2019
|b Elsevier Science
336 7 _ |a article
|2 DRIVER
336 7 _ |a Output Types/Journal article
|2 DataCite
336 7 _ |a Journal Article
|b journal
|m journal
|0 PUB:(DE-HGF)16
|s 1582281992_27335
|2 PUB:(DE-HGF)
336 7 _ |a ARTICLE
|2 BibTeX
336 7 _ |a JOURNAL_ARTICLE
|2 ORCID
336 7 _ |a Journal Article
|0 0
|2 EndNote
520 _ _ |a We estimated the association of changes in body weight, waist circumference (WC), fat mass (FM) and fat-free mass (FFM) with changes in blood pressure and incident hypertension using data from four German population-based studies.We analyzed data from 4467 participants, aged 21 to 82 years not taking antihypertensive medication and not having type 2 diabetes mellitus or a history of myocardial infarction at baseline and follow-up, from four population-based studies conducted in Germany. Body weight, WC, and blood pressure were measured at baseline and follow-up (median follow-up of the single studies 4 to 7 years). FM and FFM were calculated based on height-weight models derived from bioelectrical impedance studies. Hypertension was defined as systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg. Confounder-adjusted linear and logistic regressions were used to associate changes in anthropometric markers with changes in blood pressure, incident hypertension, and incident normalization of blood pressure.In a pooled dataset including all four studies, increments in body weight, WC, FM, and FFM were statistically significantly associated with incident hypertension and changes in systolic and diastolic blood pressure over time. Decreases in body weight, FM, and FFM were significantly associated with incident normalization of blood pressure.Our data suggests that the well-established association between obesity and blood pressure levels might be more related to body composition rather than to total body weight per se. Our findings indicate that gaining or losing FFM has substantial impact on the development or reversion of hypertension.
536 _ _ |a 323 - Metabolic Dysfunction as Risk Factor (POF3-323)
|0 G:(DE-HGF)POF3-323
|c POF3-323
|f POF III
|x 0
588 _ _ |a Dataset connected to CrossRef, PubMed,
700 1 _ |a Werner, Nicole
|b 1
700 1 _ |a Lieb, Wolfgang
|b 2
700 1 _ |a Merz, Benedikt
|b 3
700 1 _ |a Nöthlings, Ute
|b 4
700 1 _ |a Kluttig, Alexander
|b 5
700 1 _ |a Tiller, Daniel
|b 6
700 1 _ |a Greiser, Karin-Halina
|0 P:(DE-He78)e0ac0d57cdb66d87f2d95ae5f6178c1b
|b 7
|u dkfz
700 1 _ |a Vogt, Susanne
|b 8
700 1 _ |a Thorand, Barbara
|b 9
700 1 _ |a Peters, Annette
|b 10
700 1 _ |a Völzke, Henry
|b 11
700 1 _ |a Dörr, Marcus
|b 12
700 1 _ |a Schipf, Sabine
|b 13
700 1 _ |a Markus, Marcello R P
|b 14
773 _ _ |a 10.1016/j.ijcard.2018.09.035
|g Vol. 274, p. 372 - 377
|0 PERI:(DE-600)1500478-8
|p 372 - 377
|t International journal of cardiology
|v 274
|y 2019
|x 0167-5273
909 C O |p VDB
|o oai:inrepo02.dkfz.de:141872
910 1 _ |a Deutsches Krebsforschungszentrum
|0 I:(DE-588b)2036810-0
|k DKFZ
|b 7
|6 P:(DE-He78)e0ac0d57cdb66d87f2d95ae5f6178c1b
913 1 _ |a DE-HGF
|l Herz-Kreislauf-Stoffwechselerkrankungen
|1 G:(DE-HGF)POF3-320
|0 G:(DE-HGF)POF3-323
|2 G:(DE-HGF)POF3-300
|v Metabolic Dysfunction as Risk Factor
|x 0
|4 G:(DE-HGF)POF
|3 G:(DE-HGF)POF3
|b Gesundheit
914 1 _ |y 2019
915 _ _ |a Nationallizenz
|0 StatID:(DE-HGF)0420
|2 StatID
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0300
|2 StatID
|b Medline
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0310
|2 StatID
|b NCBI Molecular Biology Database
915 _ _ |a JCR
|0 StatID:(DE-HGF)0100
|2 StatID
|b INT J CARDIOL : 2017
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0200
|2 StatID
|b SCOPUS
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0600
|2 StatID
|b Ebsco Academic Search
915 _ _ |a Peer Review
|0 StatID:(DE-HGF)0030
|2 StatID
|b ASC
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0199
|2 StatID
|b Clarivate Analytics Master Journal List
915 _ _ |a WoS
|0 StatID:(DE-HGF)0110
|2 StatID
|b Science Citation Index
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0150
|2 StatID
|b Web of Science Core Collection
915 _ _ |a WoS
|0 StatID:(DE-HGF)0111
|2 StatID
|b Science Citation Index Expanded
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1110
|2 StatID
|b Current Contents - Clinical Medicine
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1030
|2 StatID
|b Current Contents - Life Sciences
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1050
|2 StatID
|b BIOSIS Previews
915 _ _ |a IF < 5
|0 StatID:(DE-HGF)9900
|2 StatID
920 1 _ |0 I:(DE-He78)C020-20160331
|k C020
|l C020 Epidemiologie von Krebs
|x 0
980 _ _ |a journal
980 _ _ |a VDB
980 _ _ |a I:(DE-He78)C020-20160331
980 _ _ |a UNRESTRICTED


LibraryCollectionCLSMajorCLSMinorLanguageAuthor
Marc 21