000141987 001__ 141987
000141987 005__ 20240229105137.0
000141987 0247_ $$2doi$$a10.1016/j.neuroscience.2017.09.041
000141987 0247_ $$2pmid$$apmid:28965836
000141987 0247_ $$2ISSN$$a0306-4522
000141987 0247_ $$2ISSN$$a1873-7544
000141987 0247_ $$2altmetric$$aaltmetric:26951593
000141987 037__ $$aDKFZ-2018-02217
000141987 041__ $$aeng
000141987 082__ $$a610
000141987 1001_ $$aBoll, S.$$b0
000141987 245__ $$aOxytocin and Pain Perception: From Animal Models to Human Research.
000141987 260__ $$aAmsterdam [u.a.]$$bElsevier Science$$c2018
000141987 3367_ $$2DRIVER$$aarticle
000141987 3367_ $$2DataCite$$aOutput Types/Journal article
000141987 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1550061214_21126$$xReview Article
000141987 3367_ $$2BibTeX$$aARTICLE
000141987 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000141987 3367_ $$00$$2EndNote$$aJournal Article
000141987 520__ $$aAn accumulating body of evidence suggests that the hypothalamic neuropeptide oxytocin (OT) has a modulatory effect on pain processing. Particularly strong evidence comes from animal models. Here, we review recent advances in animal research on the analgesic effects of OT and discuss possible target sites of OT within descending and ascending pain pathways in the brain. In addition to the spinal cord being a direct target of the neuropeptide, OT has also been shown to modulate the neuronal activity of limbic and cortical brain regions, which play a major role in the cognitive and emotional processing of pain. Human studies investigating the influence of OT on pain perception are less numerous and have revealed less consistent results. The human literature is therefore scanned thoroughly and different approaches to study the effects of OT on pain perception in humans are discussed. Moreover, we also address how OT might alleviate pain by influencing socio-emotional components in humans. We conclude that further investigating specific OT and OT-sensitive circuits, which modulate pain processing especially in primates, will improve our understanding of OT-analgesic effects. In human research, the increased use of neuroimaging and autonomic measures might help to bridge the gap to animal studies.
000141987 536__ $$0G:(DE-HGF)POF3-319H$$a319H - Addenda (POF3-319H)$$cPOF3-319H$$fPOF III$$x0
000141987 588__ $$aDataset connected to CrossRef, PubMed,
000141987 7001_ $$0P:(DE-He78)8893756c70ef48979a7cf528fd8ef0b4$$aAlmeida de Minas, A. C.$$b1$$udkfz
000141987 7001_ $$0P:(DE-He78)1c7fbe1e3965352d9b7ba228792cce3c$$aRaftogianni, A.$$b2$$udkfz
000141987 7001_ $$aHerpertz, S. C.$$b3
000141987 7001_ $$0P:(DE-He78)b2142a2557ce071790760d0126e259d3$$aGrinevich, Valery$$b4$$eLast author$$udkfz
000141987 773__ $$0PERI:(DE-600)1498423-4$$a10.1016/j.neuroscience.2017.09.041$$gVol. 387, p. 149 - 161$$p149 - 161$$tNeuroscience$$v387$$x0306-4522$$y2018
000141987 909CO $$ooai:inrepo02.dkfz.de:141987$$pVDB
000141987 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)8893756c70ef48979a7cf528fd8ef0b4$$aDeutsches Krebsforschungszentrum$$b1$$kDKFZ
000141987 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)1c7fbe1e3965352d9b7ba228792cce3c$$aDeutsches Krebsforschungszentrum$$b2$$kDKFZ
000141987 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)b2142a2557ce071790760d0126e259d3$$aDeutsches Krebsforschungszentrum$$b4$$kDKFZ
000141987 9131_ $$0G:(DE-HGF)POF3-319H$$1G:(DE-HGF)POF3-310$$2G:(DE-HGF)POF3-300$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lKrebsforschung$$vAddenda$$x0
000141987 9141_ $$y2018
000141987 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz
000141987 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline
000141987 915__ $$0StatID:(DE-HGF)0310$$2StatID$$aDBCoverage$$bNCBI Molecular Biology Database
000141987 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bNEUROSCIENCE : 2017
000141987 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS
000141987 915__ $$0StatID:(DE-HGF)0600$$2StatID$$aDBCoverage$$bEbsco Academic Search
000141987 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bASC
000141987 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List
000141987 915__ $$0StatID:(DE-HGF)0110$$2StatID$$aWoS$$bScience Citation Index
000141987 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection
000141987 915__ $$0StatID:(DE-HGF)0111$$2StatID$$aWoS$$bScience Citation Index Expanded
000141987 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences
000141987 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews
000141987 915__ $$0StatID:(DE-HGF)9900$$2StatID$$aIF < 5
000141987 9201_ $$0I:(DE-He78)V078-20160331$$kV078$$lAG Neuropeptide$$x0
000141987 980__ $$ajournal
000141987 980__ $$aVDB
000141987 980__ $$aI:(DE-He78)V078-20160331
000141987 980__ $$aUNRESTRICTED