000142037 001__ 142037 000142037 005__ 20240229105140.0 000142037 0247_ $$2doi$$a10.1001/jamaoncol.2018.2706 000142037 0247_ $$2pmid$$apmid:29860482 000142037 0247_ $$2pmc$$apmc:PMC6248091 000142037 0247_ $$2ISSN$$a2374-2437 000142037 0247_ $$2ISSN$$a2374-2445 000142037 0247_ $$2altmetric$$aaltmetric:43183335 000142037 037__ $$aDKFZ-2018-02267 000142037 041__ $$aeng 000142037 082__ $$a610 000142037 1001_ $$aGlobal Burden of Disease Cancer Collaboration$$b0$$eCollaboration Author 000142037 245__ $$aGlobal, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2016: A Systematic Analysis for the Global Burden of Disease Study. 000142037 260__ $$aChicago, Ill.$$bAmerican Medical Association$$c2018 000142037 3367_ $$2DRIVER$$aarticle 000142037 3367_ $$2DataCite$$aOutput Types/Journal article 000142037 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1549885966_1500 000142037 3367_ $$2BibTeX$$aARTICLE 000142037 3367_ $$2ORCID$$aJOURNAL_ARTICLE 000142037 3367_ $$00$$2EndNote$$aJournal Article 000142037 520__ $$aThe increasing burden due to cancer and other noncommunicable diseases poses a threat to human development, which has resulted in global political commitments reflected in the Sustainable Development Goals as well as the World Health Organization (WHO) Global Action Plan on Non-Communicable Diseases. To determine if these commitments have resulted in improved cancer control, quantitative assessments of the cancer burden are required.To assess the burden for 29 cancer groups over time to provide a framework for policy discussion, resource allocation, and research focus.Cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life-years (DALYs) were evaluated for 195 countries and territories by age and sex using the Global Burden of Disease study estimation methods. Levels and trends were analyzed over time, as well as by the Sociodemographic Index (SDI). Changes in incident cases were categorized by changes due to epidemiological vs demographic transition.In 2016, there were 17.2 million cancer cases worldwide and 8.9 million deaths. Cancer cases increased by 28% between 2006 and 2016. The smallest increase was seen in high SDI countries. Globally, population aging contributed 17%; population growth, 12%; and changes in age-specific rates, -1% to this change. The most common incident cancer globally for men was prostate cancer (1.4 million cases). The leading cause of cancer deaths and DALYs was tracheal, bronchus, and lung cancer (1.2 million deaths and 25.4 million DALYs). For women, the most common incident cancer and the leading cause of cancer deaths and DALYs was breast cancer (1.7 million incident cases, 535 000 deaths, and 14.9 million DALYs). In 2016, cancer caused 213.2 million DALYs globally for both sexes combined. Between 2006 and 2016, the average annual age-standardized incidence rates for all cancers combined increased in 130 of 195 countries or territories, and the average annual age-standardized death rates decreased within that timeframe in 143 of 195 countries or territories.Large disparities exist between countries in cancer incidence, deaths, and associated disability. Scaling up cancer prevention and ensuring universal access to cancer care are required for health equity and to fulfill the global commitments for noncommunicable disease and cancer control. 000142037 536__ $$0G:(DE-HGF)POF3-313$$a313 - Cancer risk factors and prevention (POF3-313)$$cPOF3-313$$fPOF III$$x0 000142037 588__ $$aDataset connected to CrossRef, PubMed, 000142037 7001_ $$aFitzmaurice, Christina$$b1 000142037 7001_ $$aAkinyemiju, Tomi F$$b2 000142037 7001_ $$aAl Lami, Faris Hasan$$b3 000142037 7001_ $$aAlam, Tahiya$$b4 000142037 7001_ $$aAlizadeh-Navaei, Reza$$b5 000142037 7001_ $$aAllen, Christine$$b6 000142037 7001_ $$aAlsharif, Ubai$$b7 000142037 7001_ $$aAlvis-Guzman, Nelson$$b8 000142037 7001_ $$aAmini, Erfan$$b9 000142037 7001_ $$aAnderson, Benjamin O$$b10 000142037 7001_ $$aAremu, Olatunde$$b11 000142037 7001_ $$aArtaman, Al$$b12 000142037 7001_ $$aAsgedom, Solomon Weldegebreal$$b13 000142037 7001_ $$aAssadi, Reza$$b14 000142037 7001_ $$aAtey, Tesfay Mehari$$b15 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