%0 Journal Article
%A Matejcic, M.
%A Lesueur, F.
%A Biessy, C.
%A Renault, A. L.
%A Mebirouk, N.
%A Yammine, S.
%A Keski-Rahkonen, P.
%A Li, K.
%A Hémon, B.
%A Weiderpass, E.
%A Rebours, V.
%A Boutron-Ruault, M. C.
%A Carbonnel, F.
%A Kaaks, Rudolf
%A Katzke, V.
%A Kuhn, T.
%A Boeing, H.
%A Trichopoulou, A.
%A Palli, D.
%A Agnoli, C.
%A Panico, S.
%A Tumino, R.
%A Sacerdote, C.
%A Quirós, J. R.
%A Duell, E. J.
%A Porta, M.
%A Sánchez, M. J.
%A Chirlaque, M. D.
%A Barricarte, A.
%A Amiano, P.
%A Ye, W.
%A Peeters, P. H.
%A Khaw, K. T.
%A Perez-Cornago, A.
%A Key, T. J.
%A Bueno-de-Mesquita, H. B.
%A Riboli, E.
%A Vineis, P.
%A Romieu, I.
%A Gunter, M. J.
%A Chajès, V.
%T Circulating plasma phospholipid fatty acids and risk of pancreatic cancer in a large European cohort.
%J International journal of cancer
%V 143
%N 10
%@ 0020-7136
%C Bognor Regis
%I Wiley-Liss
%M DKFZ-2018-02319
%P 2437 - 2448
%D 2018
%X There are both limited and conflicting data on the role of dietary fat and specific fatty acids in the development of pancreatic cancer. In this study, we investigated the association between plasma phospholipid fatty acids and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. The fatty acid composition was measured by gas chromatography in plasma samples collected at recruitment from375 incident pancreatic cancer cases and375 matched controls. Associations of specific fatty acids with pancreatic cancer risk were evaluated using multivariable conditional logistic regression models with adjustment for established pancreatic cancer risk factors. Statistically significant inverse associations were found between pancreatic cancer incidence and levels of heptadecanoic acid (ORT3-T1 [odds ratio for highest versus lowest tertile] =0.63; 95
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:30110135
%R 10.1002/ijc.31797
%U https://inrepo02.dkfz.de/record/142089