TY  - JOUR
AU  - Matejcic, M.
AU  - Lesueur, F.
AU  - Biessy, C.
AU  - Renault, A. L.
AU  - Mebirouk, N.
AU  - Yammine, S.
AU  - Keski-Rahkonen, P.
AU  - Li, K.
AU  - Hémon, B.
AU  - Weiderpass, E.
AU  - Rebours, V.
AU  - Boutron-Ruault, M. C.
AU  - Carbonnel, F.
AU  - Kaaks, Rudolf
AU  - Katzke, V.
AU  - Kuhn, T.
AU  - Boeing, H.
AU  - Trichopoulou, A.
AU  - Palli, D.
AU  - Agnoli, C.
AU  - Panico, S.
AU  - Tumino, R.
AU  - Sacerdote, C.
AU  - Quirós, J. R.
AU  - Duell, E. J.
AU  - Porta, M.
AU  - Sánchez, M. J.
AU  - Chirlaque, M. D.
AU  - Barricarte, A.
AU  - Amiano, P.
AU  - Ye, W.
AU  - Peeters, P. H.
AU  - Khaw, K. T.
AU  - Perez-Cornago, A.
AU  - Key, T. J.
AU  - Bueno-de-Mesquita, H. B.
AU  - Riboli, E.
AU  - Vineis, P.
AU  - Romieu, I.
AU  - Gunter, M. J.
AU  - Chajès, V.
TI  - Circulating plasma phospholipid fatty acids and risk of pancreatic cancer in a large European cohort.
JO  - International journal of cancer
VL  - 143
IS  - 10
SN  - 0020-7136
CY  - Bognor Regis
PB  - Wiley-Liss
M1  - DKFZ-2018-02319
SP  - 2437 - 2448
PY  - 2018
AB  - There are both limited and conflicting data on the role of dietary fat and specific fatty acids in the development of pancreatic cancer. In this study, we investigated the association between plasma phospholipid fatty acids and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. The fatty acid composition was measured by gas chromatography in plasma samples collected at recruitment from375 incident pancreatic cancer cases and375 matched controls. Associations of specific fatty acids with pancreatic cancer risk were evaluated using multivariable conditional logistic regression models with adjustment for established pancreatic cancer risk factors. Statistically significant inverse associations were found between pancreatic cancer incidence and levels of heptadecanoic acid (ORT3-T1 [odds ratio for highest versus lowest tertile] =0.63; 95
LB  - PUB:(DE-HGF)16
C6  - pmid:30110135
DO  - DOI:10.1002/ijc.31797
UR  - https://inrepo02.dkfz.de/record/142089
ER  -