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@ARTICLE{Sen:142133,
author = {A. Sen and N. Papadimitriou and P. Lagiou and A.
Perez-Cornago and R. C. Travis and T. J. Key and N. Murphy
and M. Gunter and H. Freisling and I. Tzoulaki and D. C.
Muller and A. J. Cross and D. S. Lopez and M. Bergmann and
H. Boeing and C. Bamia and A. Kotanidou and A. Karakatsani
and A. Tjønneland and C. Kyrø and M. Outzen and M.-L.
Redondo and V. Cayssials and M.-D. Chirlaque and A.
Barricarte and M.-J. Sánchez and N. Larrañaga and R.
Tumino and S. Grioni and D. Palli and S. Caini and C.
Sacerdote and B. Bueno-de-Mesquita and T. Kühn$^*$ and R.
Kaaks$^*$ and L. M. Nilsson and R. Landberg and P.
Wallström and I. Drake and B. H. Bech and K. Overvad and D.
Aune and K.-T. Khaw and E. Riboli and D. Trichopoulos and A.
Trichopoulou and K. K. Tsilidis},
title = {{C}offee and tea consumption and risk of prostate cancer in
the {E}uropean {P}rospective {I}nvestigation into {C}ancer
and {N}utrition.},
journal = {International journal of cancer},
volume = {144},
number = {2},
issn = {0020-7136},
address = {Bognor Regis},
publisher = {Wiley-Liss},
reportid = {DKFZ-2018-02363},
pages = {240 - 250},
year = {2019},
abstract = {The epidemiological evidence regarding the association of
coffee and tea consumption with prostate cancer risk is
inconclusive, and few cohort studies have assessed these
associations by disease stage and grade. We examined the
associations of coffee (total, caffeinated and
decaffeinated) and tea intake with prostate cancer risk in
the European Prospective Investigation into Cancer and
Nutrition. Among 142,196 men, 7,036 incident prostate cancer
cases were diagnosed over 14 years of follow-up. Data on
coffee and tea consumption were collected through validated
country-specific food questionnaires at baseline. We used
Cox proportional hazards regression models to compute hazard
ratios (HRs) and $95\%$ confidence intervals (CI). Models
were stratified by center and age, and adjusted for
anthropometric, lifestyle and dietary factors. Median coffee
and tea intake were 375 and 106 mL/day, respectively, but
large variations existed by country. Comparing the highest
(median of 855 mL/day) versus lowest (median of 103 mL/day)
consumers of coffee and tea (450 vs. 12 mL/day) the HRs were
1.02 $(95\%$ CI, 0.94-1.09) and 0.98 $(95\%$ CI, 0.90-1.07)
for risk of total prostate cancer and 0.97 $(95\%$ CI,
0.79-1.21) and 0.89 $(95\%$ CI, 0.70-1.13) for risk of fatal
disease, respectively. No evidence of association was seen
for consumption of total, caffeinated or decaffeinated
coffee or tea and risk of total prostate cancer or cancer by
stage, grade or fatality in this large cohort. Further
investigations are needed to clarify whether an association
exists by different preparations or by concentrations and
constituents of these beverages.},
cin = {C020},
ddc = {610},
cid = {I:(DE-He78)C020-20160331},
pnm = {313 - Cancer risk factors and prevention (POF3-313)},
pid = {G:(DE-HGF)POF3-313},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:29943826},
doi = {10.1002/ijc.31634},
url = {https://inrepo02.dkfz.de/record/142133},
}