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000142195 0247_ $$2doi$$a10.1136/neurintsurg-2018-013752
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000142195 0247_ $$2ISSN$$a1759-8478
000142195 0247_ $$2ISSN$$a1759-8486
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000142195 037__ $$aDKFZ-2019-00009
000142195 041__ $$aeng
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000142195 1001_ $$aVollherbst, Dominik F$$b0
000142195 245__ $$aExtra-small dual-lumen micro-balloon catheters can improve endovascular embolization: an experimental in vivo and in vitro study.
000142195 260__ $$aLondon$$bBMJ Journals$$c2018
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000142195 520__ $$aThe embolization technique can have significant impact on the success of endovascular embolization.To evaluate the feasibility, embolization characteristics, and embolization extent with a newly developed extra-small micro-balloon catheter in an in vivo and in an in vitro embolization model in comparison with standard microcatheter embolizations.Twenty-eight embolization procedures were performed in the porcine rete mirabile (RM) and in an in vitro embolization model, using either an extra-small (distal outer diameter 1.6 F) dual-lumen micro-balloon catheter or a standard microcatheter. Precipitating hydrophobic injectable liquid (PHIL) was used as embolic agent. Procedure times, number of injections, required volume of embolic agent, and embolization extent (percentage of embolized RM in postinterventional X-ray scans or number of filled sections of the in vitro model) were assessed. Histopathological analyses were performed.Total procedure time was significantly shorter (in vivo: 123 s vs 615 s (medians), P=0.001; in vitro: 180 s vs 496 s (medians), P=0.001), number of reflux events was significantly lower (in vivo: 0 vs 9 (medians), P=0.001; in vitro: 0 vs 3 (medians), P=0.001), and embolization extent was significantly higher (in vivo: 96.9% vs 65.6% (medians), P=0.011; in vitro: 26 vs 18 filled sections (medians); P=0.041) for the micro-balloon catheter groups. There was antegrade movement of the PHIL cast after balloon deflation in one in vitro embolization procedure and spontaneous balloon deflation with subsequent reflux in one in vivo embolization procedure.Extra-small dual-lumen micro-balloon catheters can improve endovascular embolization in comparison with standard microcatheter embolization.
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000142195 7001_ $$aOtto, Ruth$$b1
000142195 7001_ $$aDo, Thuy D$$b2
000142195 7001_ $$0P:(DE-He78)a8a10626a848d31e70cfd96a133cc144$$avon Deimling, Andreas$$b3$$udkfz
000142195 7001_ $$aKauczor, Hans U$$b4
000142195 7001_ $$aBendszus, Martin$$b5
000142195 7001_ $$aSommer, Christof M$$b6
000142195 7001_ $$aMöhlenbruch, Markus A$$b7
000142195 773__ $$0PERI:(DE-600)2506028-4$$a10.1136/neurintsurg-2018-013752$$gVol. 10, no. 11, p. 1092 - 1096$$n11$$p1092 - 1096$$tJournal of neuroInterventional surgery$$v10$$x1759-8486$$y2018
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