%0 Journal Article
%A Nowak, Johannes
%A Nemes, Karolina
%A Hohm, Annika
%A Vandergrift, Lindsey A
%A Hasselblatt, Martin
%A Johann, Pascal
%A Kool, Marcel
%A Frühwald, Michael C
%A Warmuth-Metz, Monika
%T Magnetic resonance imaging surrogates of molecular subgroups in atypical teratoid/rhabdoid tumor.
%J Neuro-Oncology
%V 20
%N 12
%@ 1523-5866
%C Oxford
%I Oxford Univ. Press
%M DKFZ-2019-00330
%P 1672 - 1679
%D 2018
%X Recently, 3 molecular subgroups of atypical teratoid/rhabdoid tumor (ATRT) were identified, but little is known of their clinical and magnetic resonance imaging (MRI) characteristics.A total of 43 patients with known molecular subgroup status (ATRT-sonic hedgehog [SHH], n = 17; ATRT-tyrosine [TYR], n = 16; ATRT-myelocytomatosis oncogene [MYC], n = 10) were retrieved from the EU-RHAB Registry and analyzed for clinical and MRI features.On MRI review, differences in preferential tumor location were confirmed, with ATRT-TYR being predominantly located infratentorially (P < 0.05). Peritumoral edema was more pronounced in ATRT-MYC compared with ATRT-SHH (P < 0.05) and ATRT-TYR (P < 0.05). Conversely, peripheral tumor cysts were found more frequently in ATRT-SHH (71
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:30010851
%2 pmc:PMC6231209
%R 10.1093/neuonc/noy111
%U https://inrepo02.dkfz.de/record/142612