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@ARTICLE{Wiskemann:142880,
      author       = {J. Wiskemann$^*$ and D. Clauss$^*$ and C. Tjaden and T.
                      Hackert and L. Schneider and C. M. Ulrich and K.
                      Steindorf$^*$},
      title        = {{P}rogressive {R}esistance {T}raining to {I}mpact
                      {P}hysical {F}itness and {B}ody {W}eight in {P}ancreatic
                      {C}ancer {P}atients: {A} {R}andomized {C}ontrolled {T}rial.},
      journal      = {Pancreas},
      volume       = {48},
      number       = {2},
      issn         = {0885-3177},
      address      = {[s.l.]},
      publisher    = {Ovid},
      reportid     = {DKFZ-2019-00510},
      pages        = {257 - 266},
      year         = {2019},
      abstract     = {Maintaining or improving muscle mass and muscle strength is
                      an important treatment goal in pancreatic cancer (PC)
                      patients because of high risk of cachexia. Therefore, we
                      assessed feasibility and effectivity of a 6-month
                      progressive resistance training (RT) in PC patients within a
                      randomized controlled trial.Sixty-five PC patients were
                      randomly assigned to either supervised progressive RT (RT1),
                      home-based RT (RT2), or usual care control group (CON). Both
                      exercise groups performed training 2 times per week for 6
                      months. Muscle strength for knee, elbow, and hip extensors
                      and flexors and cardiorespiratory fitness and body weight
                      were assessed before and after the intervention period.Of 65
                      patients, 43 patients were analyzed. Adherence rates were
                      $64.1\%$ (RT1) and $78.4\%$ (RT2) of the prescribed training
                      sessions. RT1 showed significant improvements in elbow
                      flexor/extensor muscle strength and in maximal work load
                      versus CON and RT2 (P < 0.05). Further, knee extensors were
                      significantly improved for RT1 versus CON (P < 0.05). Body
                      weight revealed no significant group differences over
                      time.Progressive RT was feasible in PC patients and improved
                      muscle strength with significant results for some muscle
                      groups. Supervised RT seemed to be more effective than
                      home-based RT.},
      cin          = {C110},
      ddc          = {610},
      cid          = {I:(DE-He78)C110-20160331},
      pnm          = {313 - Cancer risk factors and prevention (POF3-313)},
      pid          = {G:(DE-HGF)POF3-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:30589829},
      doi          = {10.1097/MPA.0000000000001221},
      url          = {https://inrepo02.dkfz.de/record/142880},
}