TY - JOUR AU - Caputo, Mahrrouz AU - Horn, Johannes AU - Karch, André AU - Akmatov, Manas K AU - Becher, Heiko AU - Braun, Bettina AU - Brenner, Hermann AU - Castell, Stefanie AU - Fischer, Beate AU - Giani, Guido AU - Günther, Kathrin AU - Hoffmann, Barbara AU - Jöckel, Karl-Heinz AU - Keil, Thomas AU - Klüppelholz, Birgit AU - Krist, Lilian AU - Leitzmann, Michael F AU - Lieb, Wolfgang AU - Linseisen, Jakob AU - Meisinger, Christa AU - Moebus, Susanne AU - Obi, Nadia AU - Pischon, Tobias AU - Schipf, Sabine AU - Schmidt, Börge AU - Sievers, Claudia AU - Steinbrecher, Astrid AU - Völzke, Henry AU - Mikolajczyk, Rafael TI - Herpes zoster incidence in Germany - an indirect validation study for self-reported disease data from pretest studies of the population-based German National Cohort. JO - BMC infectious diseases VL - 19 IS - 1 SN - 1471-2334 CY - Heidelberg PB - Springer M1 - DKFZ-2019-00556 SP - 99 PY - 2019 AB - Until now, herpes zoster (HZ)-related disease burden in Germany has been estimated based on health insurance data and clinical findings. However, the validity of self-reported HZ is unclear. This study investigated the validity of self-reported herpes zoster (HZ) and its complication postherpetic neuralgia (PHN) using data from the pretest studies of the German National Cohort (GNC) in comparison with estimates based on health insurance data.Data of 4751 participants aged between 20 and 69 years from two pretest studies of the GNC carried out in 2011 and 2012 were used. Based on self-reports of physician-diagnosed HZ and PHN, age- and sex-specific HZ incidence rates and PHN proportions were estimated. For comparison, estimates based on statutory health insurance data from the German population were considered.Eleven percent (95 LB - PUB:(DE-HGF)16 C6 - pmid:30700258 C2 - pmc:PMC6354372 DO - DOI:10.1186/s12879-019-3691-2 UR - https://inrepo02.dkfz.de/record/142928 ER -