TY  - JOUR
AU  - Balavarca Villanueva, Yesilda
AU  - Weigl, Korbinian
AU  - Thomsen, Hauke
AU  - Brenner, Hermann
TI  - Performance of individual and joint risk stratification by an environmental risk score and a genetic risk score in a colorectal cancer screening setting.
JO  - International journal of cancer
VL  - 146
IS  - 3
SN  - 1097-0215
CY  - Bognor Regis
PB  - Wiley-Liss
M1  - DKFZ-2019-00768
SP  - 627-634
PY  - 2020
N1  - 2020 Feb 1;146(3):627-634#EA:C120#LA:C120#
AB  - Early detection of colorectal neoplasms can reduce the disease burden of colorectal cancer by timely intervention of individuals at high risk. Our aim was to evaluate a joint environmental-genetic risk score as a risk stratification tool for early detection of advanced colorectal neoplasm (ACRN). Known environmental risk factors and high-risk genetic loci were summarized into risk scores for ACRN in 1014 eligible participants of a screening study. The performances of single and joint environmental-genetic scores were evaluated with estimates and 95
LB  - PUB:(DE-HGF)16
C6  - pmid:30868574
DO  - DOI:10.1002/ijc.32272
UR  - https://inrepo02.dkfz.de/record/143169
ER  -