TY  - JOUR
AU  - Krilaviciute, Agne
AU  - Leja, Marcis
AU  - Kopp-Schneider, Annette
AU  - Barash, Orna
AU  - Khatib, Salam
AU  - Amal, Haitham
AU  - Broza, Yoav Y
AU  - Polaka, Inese
AU  - Parshutin, Sergei
AU  - Rudule, Aiga
AU  - Haick, Hossam
AU  - Brenner, Hermann
TI  - Associations of diet and lifestyle factors with common volatile organic compounds in exhaled breath of average-risk individuals.
JO  - Journal of breath research
VL  - 13
IS  - 2
SN  - 1752-7163
CY  - Bristol
PB  - IOP
M1  - DKFZ-2019-00771
SP  - 026006
PY  - 2019
AB  - Detection of diseases via exhaled breath remains an attractive idea despite persisting gaps in understanding the origin of volatile organic compounds (VOCs) and their relationship with the disease of interest. Data on factors potentially influencing the results of breath analysis remain rather sparse and often controversial. In this study, we aimed to investigate the associations of common VOCs in exhaled breath of average-risk individuals with socio-demographic and lifestyle factors, medical conditions as well as diet.Alveolar breath samples of 1447 men and women were collected in the morning after fasting and were analyzed using gas-chromatography linked with mass-spectrometry. Study participants were 40-64 years old, cancer-free, with overall good health status. The associations between selected VOCs and various factors determined from the questionnaire data were assessed using two-part-Wilcoxon test and Jonckheere-Terpstra trend test.Fifteen VOCs where each of them was detected in at least 80
LB  - PUB:(DE-HGF)16
C6  - pmid:30523935
DO  - DOI:10.1088/1752-7163/aaf3dc
UR  - https://inrepo02.dkfz.de/record/143172
ER  -