TY  - JOUR
AU  - Boehlen, Friederike H
AU  - Freigofas, Julia
AU  - Herzog, Wolfgang
AU  - Meid, Andreas D
AU  - Saum, Kai-Uwe
AU  - Schoettker, Ben
AU  - Brenner, Hermann
AU  - Haefeli, Walter E
AU  - Wild, Beate
TI  - Evidence for underuse and overuse of antidepressants in older adults: Results of a large population-based study.
JO  - International journal of geriatric psychiatry
VL  - 34
IS  - 4
SN  - 1099-1166
CY  - Chichester [u.a.]
PB  - Wiley
M1  - DKFZ-2019-00806
SP  - 539 - 547
PY  - 2019
AB  - Depression is common among elderly people. However, diagnosis and adequate treatment is frequently difficult. Research on underuse and overuse of antidepressants in elderly persons is scarce. This study investigates the utilization and appropriateness of pharmacological and psychological depression treatment in a large cohort of community-dwelling adults.A subsample of 3117 participants (aged 55-85 y) of the third follow-up (2008-2010) of the large population-based German ESTHER study was included. Depression was assessed using the eight-item Patient Health Questionnaire (PHQ-8). In the course of a home visit, study doctors collected complete information on medication. Logistic regression analyses were conducted to determine the relationship of depression with both underuse and overuse of antidepressants. The analyses were then adjusted for socioeconomic variables, psychosomatic comorbidities, and motivation to seek help.One hundred sixty-three participants (5.2
LB  - PUB:(DE-HGF)16
C6  - pmid:30623499
DO  - DOI:10.1002/gps.5047
UR  - https://inrepo02.dkfz.de/record/143207
ER  -