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@ARTICLE{Brunssen:143209,
      author       = {A. Brunssen and L. Jansen$^*$ and N. Eisemann and A.
                      Waldmann and J. Weberpals$^*$ and K. Kraywinkel and A.
                      Eberle and B. Holleczek and S. R. Zeissig and H. Brenner$^*$
                      and A. Katalinic and K. Geiss and M. Meyer and S. Luttmann
                      and R. Stabenow and S. Hentschel and A. Nennecke and J.
                      Kieschke and E. Sirri and K. Emrich and H. Kajüter and V.
                      Mattauch},
      collaboration = {G. C. S. W. Group},
      title        = {{A} population-based registry study on relative survival
                      from melanoma in {G}ermany stratified by tumor thickness for
                      each histologic subtype.},
      journal      = {Journal of the American Academy of Dermatology},
      volume       = {80},
      number       = {4},
      issn         = {0190-9622},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier},
      reportid     = {DKFZ-2019-00808},
      pages        = {938 - 946},
      year         = {2019},
      abstract     = {Differences in relative survival (RS) of melanoma between
                      histologic subtypes were discussed to be mainly caused by
                      tumor thickness.To investigate RS of melanoma, stratified by
                      tumor thickness for each histologic subtype, and identify
                      survival trends.With use of cancer registry data on melanoma
                      cases (International Classification of Diseases, 10th
                      Revision, codes C43.0-C43.9) diagnosed in Germany in
                      1997-2013, 5- and 10-year age-standardized RS stratified by
                      histologic subtype and stratified or standardized by T stage
                      was estimated by standard and modeled period analyses. We
                      restricted 10-year RS analyses to patients younger than
                      75 years.We analyzed 82,901 cases. Overall, the 5- and
                      10-year RS rates were $91.7\%$ and $90.8\%,$ respectively.
                      Prognosis worsened with increasing T stage for all
                      histologic subtypes, but T-stage distribution varied
                      substantially. Survival differences by histologic subtype
                      were strongly alleviated after adjustment for T stage but
                      remained significant. Overall, 5-year RS increased
                      significantly (by 3.8 percentage points) between the periods
                      2002-2005 and 2010-2013. This increase was no longer seen
                      after adjustment for T stage.Exclusion of cases on account
                      of missing information on T stages, changes in the
                      definition of T stages, and lack of information on screening
                      and treatment limit our analyses.Differences in RS between
                      histologic subtypes were strongly mediated by tumor
                      thickness. Over time, RS of melanoma increased as a result
                      of changes in T-stage distribution.},
      cin          = {C070 / L101},
      ddc          = {610},
      cid          = {I:(DE-He78)C070-20160331 / I:(DE-He78)L101-20160331},
      pnm          = {313 - Cancer risk factors and prevention (POF3-313)},
      pid          = {G:(DE-HGF)POF3-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:30244061},
      doi          = {10.1016/j.jaad.2018.09.018},
      url          = {https://inrepo02.dkfz.de/record/143209},
}