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@ARTICLE{Negaresh:143238,
      author       = {R. Negaresh and R. Motl and M. Mokhtarzade and R. Ranjbar
                      and N. Majdinasab and M. Khodadoost and P. Zimmer$^*$ and J.
                      S. Baker and D. Patel},
      title        = {{E}ffect of {S}hort-{T}erm {I}nterval {E}xercise {T}raining
                      on {F}atigue, {D}epression, and {F}itness in {N}ormal
                      {W}eight vs. {O}verweight {P}erson {W}ith {M}ultiple
                      {S}clerosis.},
      journal      = {Explore},
      volume       = {15},
      number       = {2},
      issn         = {1550-8307},
      address      = {New York, NY},
      publisher    = {Elsevier},
      reportid     = {DKFZ-2019-00836},
      pages        = {134 - 141},
      year         = {2019},
      abstract     = {Excessive weight is a health problem that can exacerbate
                      multiple sclerosis (MS) symptoms and its associated
                      comorbidities such as depression and fatigue. In addition,
                      weight may be a moderator of exercise effects on depression
                      and fatigue symptoms.This study aimed to investigate the
                      effects of exercise training on fatigue and depression in
                      normal and overweight individuals with MS.Sixty-six persons
                      with MS were randomly assigned into an exercise or control
                      condition based on body weight status (overweight vs. normal
                      weight). The exercise conditions involved 8-weeks of
                      interval exercise at $60\%-75\%$ Wattpeak, while the control
                      condition did not involve any exercise. Fatigue, depression,
                      aerobic capacity, time up and go (TUG) and body mass index
                      were measured before and following the 8-week period.There
                      were no significant relationship's revealed for weight
                      status interactions for any of the variables examined. There
                      were significant condition main effects for fatigue,
                      depression, aerobic capacity and TUG, and significant
                      improvements were noted for the exercise conditions, but not
                      in the non-exercising control group.The results from this
                      study confirm that exercise is an effective therapeutic
                      intervention for improving fatigue, depression and
                      functional parameters, independent of initial weight status,
                      in persons with MS.},
      cin          = {C110},
      ddc          = {610},
      cid          = {I:(DE-He78)C110-20160331},
      pnm          = {313 - Cancer risk factors and prevention (POF3-313)},
      pid          = {G:(DE-HGF)POF3-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:30122328},
      doi          = {10.1016/j.explore.2018.07.007},
      url          = {https://inrepo02.dkfz.de/record/143238},
}