TY  - JOUR
AU  - Tian, Yu
AU  - Kharazmi, Elhamalsadat
AU  - Sundquist, Kristina
AU  - Sundquist, Jan
AU  - Brenner, Hermann
AU  - Fallah, Mahdi
TI  - Familial colorectal cancer risk in half siblings and siblings: nationwide cohort study.
JO  - The BMJ
VL  - 364
SN  - 0959-8138
CY  - London
PB  - British Medical Association56099
M1  - DKFZ-2019-00840
SP  - l803
PY  - 2019
AB  - To explore the risk of colorectal cancer in family members of patients with colorectal cancer, with an emphasis on subtypes of second degree relatives, especially half siblings, which were lacking in the literature.Ambidirectional cohort study.Nationwide Swedish Family Cancer Data (record linkage).All people residing in Sweden and born after 1931, with their biological parents, totalling >16 million individuals (follow-up: 1958-2015); of those with clear genealogy, 173 796 developed colorectal cancer.Lifetime (0-79 years) cumulative risk and standardised incidence ratio of colorectal cancer among first degree relatives and second degree relatives.The overall lifetime cumulative risk of colorectal cancer in siblings of patients was 7
LB  - PUB:(DE-HGF)16
C6  - pmid:30872356
DO  - DOI:10.1136/bmj.l803
UR  - https://inrepo02.dkfz.de/record/143242
ER  -