%0 Journal Article
%A Schübel, Ruth
%A Nonnenmacher, Tobias
%A Sookthai, Disorn
%A Gonzalez Maldonado, Sandra
%A Sowah, Solomon A
%A von Stackelberg, Oyunbileg
%A Schlett, Christopher L
%A Grafetstätter, Mirja
%A Nabers, Diana
%A Johnson, Theron Scot
%A Kirsten, Romy
%A Ulrich, Cornelia M
%A Kaaks, Rudolf
%A Kauczor, Hans-Ulrich
%A Kühn, Tilman
%A Nattenmüller, Johanna
%T Similar Weight Loss Induces Greater Improvements in Insulin Sensitivity and Liver Function among Individuals with NAFLD Compared to Individuals without NAFLD.
%J Nutrients
%V 11
%N 3
%@ 2072-6643
%C Basel
%I MDPI
%M DKFZ-2019-01063
%P 544 
%D 2019
%X Preliminary evidence suggests that weight loss among obese has differential metabolic effects depending on the presence of non-alcoholic fatty liver disease (NAFLD). We assessed whether NAFLD predisposes to differential changes in liver fat content, liver function, and metabolic parameters upon diet-induced weight loss in a 50-week intervention trial.143 overweight and obese non-smokers underwent a 12-week dietary intervention and a 38-week follow-up. Diet-induced changes in anthropometric measures, circulating biomarkers, and magnetic resonance (MR)-derived liver fat content and adipose tissue volumes were evaluated by mixed linear models stratifying by NAFLD at baseline.The prevalence of NAFLD at baseline was 52
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:30836637
%R 10.3390/nu11030544
%U https://inrepo02.dkfz.de/record/143475