TY  - JOUR
AU  - Schübel, Ruth
AU  - Nonnenmacher, Tobias
AU  - Sookthai, Disorn
AU  - Gonzalez Maldonado, Sandra
AU  - Sowah, Solomon A
AU  - von Stackelberg, Oyunbileg
AU  - Schlett, Christopher L
AU  - Grafetstätter, Mirja
AU  - Nabers, Diana
AU  - Johnson, Theron Scot
AU  - Kirsten, Romy
AU  - Ulrich, Cornelia M
AU  - Kaaks, Rudolf
AU  - Kauczor, Hans-Ulrich
AU  - Kühn, Tilman
AU  - Nattenmüller, Johanna
TI  - Similar Weight Loss Induces Greater Improvements in Insulin Sensitivity and Liver Function among Individuals with NAFLD Compared to Individuals without NAFLD.
JO  - Nutrients
VL  - 11
IS  - 3
SN  - 2072-6643
CY  - Basel
PB  - MDPI
M1  - DKFZ-2019-01063
SP  - 544 
PY  - 2019
AB  - Preliminary evidence suggests that weight loss among obese has differential metabolic effects depending on the presence of non-alcoholic fatty liver disease (NAFLD). We assessed whether NAFLD predisposes to differential changes in liver fat content, liver function, and metabolic parameters upon diet-induced weight loss in a 50-week intervention trial.143 overweight and obese non-smokers underwent a 12-week dietary intervention and a 38-week follow-up. Diet-induced changes in anthropometric measures, circulating biomarkers, and magnetic resonance (MR)-derived liver fat content and adipose tissue volumes were evaluated by mixed linear models stratifying by NAFLD at baseline.The prevalence of NAFLD at baseline was 52
LB  - PUB:(DE-HGF)16
C6  - pmid:30836637
DO  - DOI:10.3390/nu11030544
UR  - https://inrepo02.dkfz.de/record/143475
ER  -