%0 Journal Article %A Bozorgmehr, Kayvan %A Preussler, Stella %A Wagner, Ulrich %A Joggerst, Brigitte %A Szecsenyi, Joachim %A Razum, Oliver %A Stock, Christian %T Using country of origin to inform targeted tuberculosis screening in asylum seekers: a modelling study of screening data in a German federal state, 2002-2015. %J BMC infectious diseases %V 19 %N 1 %@ 1471-2334 %C Heidelberg %I Springer %M DKFZ-2019-01089 %P 304 %D 2019 %X Screening programmes for tuberculosis (TB) among immigrants rarely consider the heterogeneity of risk related to migrants' country of origin. We assess the performance of a large screening programme in asylum seekers by analysing (i) the difference in yield and numbers needed to screen (NNS) by country and WHO-reported TB burden, (ii) the possible impact of screening thresholds on sensitivity, and (iii) the value of WHO-estimated TB burden to improve the prediction accuracy of screening yield.We combined individual data of 119,037 asylum seekers screened for TB in Germany (2002-2015) with TB estimates of the World Health Organization (WHO) (1990-2014) for their 81 countries of origin. Adjusted rate ratios (aRR) and 95 %F PUB:(DE-HGF)16 %9 Journal Article %$ pmid:30943917 %2 pmc:PMC6448304 %R 10.1186/s12879-019-3902-x %U https://inrepo02.dkfz.de/record/143505