%0 Journal Article
%A Chen, Hongda
%A Stock, Christian
%A Hoffmeister, Michael
%A Brenner, Hermann
%T Optimal age for screening colonoscopy: a modeling study.g110
%J Gastrointestinal endoscopy
%V 89
%N 5
%@ 0016-5107
%C New York, NY
%I Elsevier
%M DKFZ-2019-01138
%P 1017 - 1025.e12
%D 2019
%X Recent guidelines on colorectal cancer (CRC) screening recommend starting screening earlier than before. We performed a simulation study to examine and compare the optimal ages to have once-only screening colonoscopy and repeated colonoscopies.A Markov model was set up using data from the German national screening colonoscopy registry to simulate the natural history of the adenoma-carcinoma process. CRC deaths and years of potential life lost (YPLL) for a hypothetical unscreened 50-year-old German population were estimated for a single screening colonoscopy or 2 or 3 screening colonoscopies with 10-year intervals at various ages.One single screening colonoscopy performed between 50 and 65 years of age was expected to reduce CRC death by 49
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:30639539
%R 10.1016/j.gie.2018.12.021
%U https://inrepo02.dkfz.de/record/143557