TY  - JOUR
AU  - Chen, Hongda
AU  - Stock, Christian
AU  - Hoffmeister, Michael
AU  - Brenner, Hermann
TI  - Optimal age for screening colonoscopy: a modeling study.g110
JO  - Gastrointestinal endoscopy
VL  - 89
IS  - 5
SN  - 0016-5107
CY  - New York, NY
PB  - Elsevier
M1  - DKFZ-2019-01138
SP  - 1017 - 1025.e12
PY  - 2019
AB  - Recent guidelines on colorectal cancer (CRC) screening recommend starting screening earlier than before. We performed a simulation study to examine and compare the optimal ages to have once-only screening colonoscopy and repeated colonoscopies.A Markov model was set up using data from the German national screening colonoscopy registry to simulate the natural history of the adenoma-carcinoma process. CRC deaths and years of potential life lost (YPLL) for a hypothetical unscreened 50-year-old German population were estimated for a single screening colonoscopy or 2 or 3 screening colonoscopies with 10-year intervals at various ages.One single screening colonoscopy performed between 50 and 65 years of age was expected to reduce CRC death by 49
LB  - PUB:(DE-HGF)16
C6  - pmid:30639539
DO  - DOI:10.1016/j.gie.2018.12.021
UR  - https://inrepo02.dkfz.de/record/143557
ER  -