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000143835 0247_ $$2ISSN$$a1435-1293
000143835 0247_ $$2ISSN$$a1436-6207
000143835 0247_ $$2ISSN$$a1436-6215
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000143835 1001_ $$00000-0002-6236-6804$$aGarro-Aguilar, Yaiza$$b0
000143835 245__ $$aCorrelations between urinary concentrations and dietary intakes of flavonols in the European Prospective Investigation into Cancer and Nutrition (EPIC) study.
000143835 260__ $$aHeidelberg$$bSpringer$$c2020
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000143835 500__ $$a2020 Jun;59(4):1481-1492
000143835 520__ $$aIn this study, we aimed to study the correlation between acute and habitual intakes of flavonols, their main food sources and their 24-h urinary concentrations in an European population.A 24-h dietary recall (24-HDR) and 24-h urine samples were collected on the same day from a convenience subsample of 475 men and women from four countries (France, Italy, Greece and Germany) of the European Prospective Investigation into Cancer and Nutrition (EPIC) study. A standardized 24-HDR software and a country/centre-specific validated dietary questionnaire (DQ) were used to collect acute and habitual dietary data, respectively. The intake of dietary flavonols was estimated using the Phenol-Explorer database. Urinary flavonols (quercetin, isorhamnetin, and kaempferol) were analysed using tandem mass spectrometry with a previous enzymatic hydrolysis.Weak partial Spearman correlations between both dietary acute and habitual intake and urinary concentrations of quercetin (both Rpartial ~ 0.3) and total flavonols (both Rpartial ~ 0.2) were observed. No significant correlations were found for kaempferol and isorhamentin. Regarding flavonol-rich foods, weak correlations were found between urinary concentrations of quercetin and total flavonols and the acute intake of onions and garlics, fruits, tea, and herbal tea (all Rpartial ~ 0.2). For habitual intake, statistically significant correlations were only found between urinary quercetin concentration and herbal tea (Rpartial = 0.345) and between urinary total flavonol concentration and tea, and herbal tea consumption (Rpartial ~ 0.2).Our results suggest that urinary quercetin level can be used as potential concentration biomarkers of both acute and habitual quercetin intake, while urinary concentrations of flavonols are unlikely to be useful biomarkers of individual flavonol-rich foods.
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000143835 7001_ $$aCayssials, Valerie$$b1
000143835 7001_ $$aAchaintre, David$$b2
000143835 7001_ $$aBoeing, Heiner$$b3
000143835 7001_ $$aMancini, Francesca Romana$$b4
000143835 7001_ $$aMahamat-Saleh, Yahya$$b5
000143835 7001_ $$aBoutron-Ruault, Marie-Christine$$b6
000143835 7001_ $$0P:(DE-He78)0907a10ba1dc8f53f04907f54f6fdcfe$$aKühn, Tilman$$b7$$udkfz
000143835 7001_ $$0P:(DE-He78)fb68a9386399d72d84f7f34cfc6048b4$$aKatzke, Verena$$b8$$udkfz
000143835 7001_ $$aTrichopoulou, Antonia$$b9
000143835 7001_ $$aKarakatsani, Anna$$b10
000143835 7001_ $$aThriskos, Paschalis$$b11
000143835 7001_ $$aMasala, Giovanna$$b12
000143835 7001_ $$aGrioni, Sara$$b13
000143835 7001_ $$aSantucci de Magistris, Maria$$b14
000143835 7001_ $$aTumino, Rosario$$b15
000143835 7001_ $$aRicceri, Fulvio$$b16
000143835 7001_ $$aHuybrechts, Inge$$b17
000143835 7001_ $$aAgudo, Antonio$$b18
000143835 7001_ $$aScalbert, Augustin$$b19
000143835 7001_ $$aZamora-Ros, Raul$$b20
000143835 773__ $$0PERI:(DE-600)1463312-7$$a10.1007/s00394-019-02005-5$$n4$$p1481-1492$$tEuropean journal of nutrition$$v59$$x1436-6215$$y2020
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