%0 Journal Article
%A Holleczek, Bernd
%A Stegmaier, Christa
%A Radosa, Julia C
%A Solomayer, Erich-Franz
%A Brenner, Hermann
%T Risk of loco-regional recurrence and distant metastases of patients with invasive breast cancer up to ten years after diagnosis - results from a registry-based study from Germany.
%J BMC cancer
%V 19
%N 1
%@ 1471-2407
%C Heidelberg
%I Springer
%M DKFZ-2019-01424
%P 520
%D 2019
%X Population-based estimates of the long-term risk of loco-regional recurrence and distant metastases of breast cancer (BRC) patients are scant, as most published studies used hospital-based cohorts or participants of clinical trials. This work aims to extend available knowledge by providing population-based long-term estimates of the cumulative risk of BRC recurrence up to 10 years after diagnosis.Data from the population-based Saarland Cancer Registry were used and included 9359 female patients with primary invasive BRC diagnosed between 1999 and 2009. Estimates of the cumulative incidence (CI) of BRC recurrence were derived for patients who had received local surgery with free resection margins by type of recurrence and stratified by age, tumor characteristics and major treatment options, taking into account mortality from any cause as a competing risk.The 10-year CI of BRC recurrence was 16
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:31146706
%R 10.1186/s12885-019-5710-5
%U https://inrepo02.dkfz.de/record/143862