000144387 001__ 144387
000144387 005__ 20240229123018.0
000144387 0247_ $$2doi$$a10.2967/jnumed.119.227637
000144387 0247_ $$2pmid$$apmid:31302638
000144387 0247_ $$2ISSN$$a0022-3123
000144387 0247_ $$2ISSN$$a0097-9058
000144387 0247_ $$2ISSN$$a0161-5505
000144387 0247_ $$2ISSN$$a1535-5667
000144387 0247_ $$2ISSN$$a2159-662X
000144387 0247_ $$2altmetric$$aaltmetric:63741874
000144387 037__ $$aDKFZ-2019-01840
000144387 041__ $$aeng
000144387 082__ $$a610
000144387 1001_ $$aKoerber, Stefan A$$b0
000144387 245__ $$aLymph node involvement in treatment-naïve prostate cancer patients - correlation of PSMA-PET/CT imaging and Roach formula in 280 men in the Radiotherapeutic management.
000144387 260__ $$aNew York, NY$$bSoc.$$c2020
000144387 3367_ $$2DRIVER$$aarticle
000144387 3367_ $$2DataCite$$aOutput Types/Journal article
000144387 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1601380741_28271
000144387 3367_ $$2BibTeX$$aARTICLE
000144387 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000144387 3367_ $$00$$2EndNote$$aJournal Article
000144387 500__ $$a2020 Jan;61(1):46-50#LA:E060#
000144387 520__ $$aThe importance of PSMA-PET/CT for primary staging of treatment-naïve prostate cancer patients is still under debate. Therefore, the present study aimed to evaluate the role of PSMA PET/CT in detecting nodal metastases in a large cohort of men and compare imaging results with the risk of lymph node involvement based on the Roach formula. Methods: In total, 280 men with newly diagnosed prostate carcinoma were included in the present study. For all patients PSMA-PET/CT was performed for primary staging. Median age was 67 years (range 38 - 84 years), 84% of all patients were classified as high-risk according to d'Amico. The risk of lymph node involvement was calculated using the Roach formula and compared to the PSMA-PET/CT results. Results: PSMA-positive nodes were detected in 90 of 280 men (32.1%). While the majority of nodal metastases occurred within the pelvis, 35.5% were observed in extrapelvic sites. In 9 patients (3.2%), nodal metastases occurred in the Virchow node. After comparison of PSMA data with the results of the Roach formula, an area under the curve (AUC) of 0.781 was obtained for the Roach predictions. Conclusion: For treatment-naïve prostate cancer patients, PSMA-PET/CT is well suited for the detection of nodal metastases. However, the original Roach formula can still be used for a quick assessment of potential lymphatic spread in daily clinical routine.
000144387 536__ $$0G:(DE-HGF)POF3-315$$a315 - Imaging and radiooncology (POF3-315)$$cPOF3-315$$fPOF III$$x0
000144387 588__ $$aDataset connected to CrossRef, PubMed,
000144387 7001_ $$aStach, Gerald$$b1
000144387 7001_ $$aKratochwil, Clemens$$b2
000144387 7001_ $$aHaefner, Matthias F$$b3
000144387 7001_ $$aRathke, Henrik$$b4
000144387 7001_ $$aHerfarth, Klaus$$b5
000144387 7001_ $$0P:(DE-He78)9793347ba83f527b81a22ab75af9378a$$aKopka, Klaus$$b6$$udkfz
000144387 7001_ $$0P:(DE-He78)457c042884c901eb0a02c18bb1d30103$$aHolland-Letz, Tim$$b7$$udkfz
000144387 7001_ $$aChoyke, Peter L$$b8
000144387 7001_ $$aWill, Leon$$b9
000144387 7001_ $$0P:(DE-He78)13a0afba029f5f64dc18b25ef7499558$$aHaberkorn, Uwe$$b10$$udkfz
000144387 7001_ $$0P:(DE-HGF)0$$aDebus, Juergen$$b11
000144387 7001_ $$0P:(DE-He78)5ca7e97b2769bb97f8c73431c6566b94$$aGiesel, Frederik$$b12$$eLast author$$udkfz
000144387 773__ $$0PERI:(DE-600)2040222-3$$a10.2967/jnumed.119.227637$$gp. jnumed.119.227637 -$$n1$$p46-50$$tJournal of nuclear medicine$$v61$$x2159-662X$$y2020
000144387 909CO $$ooai:inrepo02.dkfz.de:144387$$pVDB
000144387 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)9793347ba83f527b81a22ab75af9378a$$aDeutsches Krebsforschungszentrum$$b6$$kDKFZ
000144387 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)457c042884c901eb0a02c18bb1d30103$$aDeutsches Krebsforschungszentrum$$b7$$kDKFZ
000144387 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)13a0afba029f5f64dc18b25ef7499558$$aDeutsches Krebsforschungszentrum$$b10$$kDKFZ
000144387 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-HGF)0$$aDeutsches Krebsforschungszentrum$$b11$$kDKFZ
000144387 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)5ca7e97b2769bb97f8c73431c6566b94$$aDeutsches Krebsforschungszentrum$$b12$$kDKFZ
000144387 9131_ $$0G:(DE-HGF)POF3-315$$1G:(DE-HGF)POF3-310$$2G:(DE-HGF)POF3-300$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lKrebsforschung$$vImaging and radiooncology$$x0
000144387 9141_ $$y2020
000144387 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bJ NUCL MED : 2017
000144387 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS
000144387 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline
000144387 915__ $$0StatID:(DE-HGF)0310$$2StatID$$aDBCoverage$$bNCBI Molecular Biology Database
000144387 915__ $$0StatID:(DE-HGF)0320$$2StatID$$aDBCoverage$$bPubMed Central
000144387 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List
000144387 915__ $$0StatID:(DE-HGF)0110$$2StatID$$aWoS$$bScience Citation Index
000144387 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection
000144387 915__ $$0StatID:(DE-HGF)0111$$2StatID$$aWoS$$bScience Citation Index Expanded
000144387 915__ $$0StatID:(DE-HGF)1110$$2StatID$$aDBCoverage$$bCurrent Contents - Clinical Medicine
000144387 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences
000144387 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews
000144387 915__ $$0StatID:(DE-HGF)9905$$2StatID$$aIF >= 5$$bJ NUCL MED : 2017
000144387 9202_ $$0I:(DE-He78)E060-20160331$$kE060$$lE060 KKE Nuklearmedizin$$x0
000144387 9201_ $$0I:(DE-He78)E060-20160331$$kE060$$lE060 KKE Nuklearmedizin$$x0
000144387 9201_ $$0I:(DE-He78)E030-20160331$$kE030$$lE030 Radiopharmazeutische Chemie$$x1
000144387 9201_ $$0I:(DE-He78)HD01-20160331$$kHD01$$lDKTK HD zentral$$x2
000144387 9201_ $$0I:(DE-He78)C060-20160331$$kC060$$lC060 Biostatistik$$x3
000144387 9201_ $$0I:(DE-He78)E050-20160331$$kE050$$lE050 KKE Strahlentherapie$$x4
000144387 980__ $$ajournal
000144387 980__ $$aVDB
000144387 980__ $$aI:(DE-He78)E060-20160331
000144387 980__ $$aI:(DE-He78)E030-20160331
000144387 980__ $$aI:(DE-He78)HD01-20160331
000144387 980__ $$aI:(DE-He78)C060-20160331
000144387 980__ $$aI:(DE-He78)E050-20160331
000144387 980__ $$aUNRESTRICTED