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@ARTICLE{Hbschmann:144470,
      author       = {D. Hübschmann$^*$ and M. Schlesner$^*$},
      title        = {{E}valuation of {W}hole {G}enome {S}equencing {D}ata.},
      journal      = {Methods in molecular biology},
      volume       = {1956},
      issn         = {1064-3745},
      address      = {[Heidelberg]},
      publisher    = {[Springer]},
      reportid     = {DKFZ-2019-01921},
      isbn         = {978-1-4939-9150-1 (print)},
      pages        = {321-336},
      year         = {2019},
      abstract     = {Whole genome sequencing (WGS) can provide comprehensive
                      insights into the genetic makeup of lymphomas. Here we
                      describe a selection of methods for the analysis of WGS
                      data, including alignment, identification of different
                      classes of genomic variants, the identification of driver
                      mutations, and the identification of mutational signatures.
                      We further outline design considerations for WGS studies and
                      provide a variety of quality control measures to detect
                      common quality problems in the data.},
      cin          = {B080 / V960 / A010 / B240},
      ddc          = {570},
      cid          = {I:(DE-He78)B080-20160331 / I:(DE-He78)V960-20160331 /
                      I:(DE-He78)A010-20160331 / I:(DE-He78)B240-20160331},
      pnm          = {312 - Functional and structural genomics (POF3-312)},
      pid          = {G:(DE-HGF)POF3-312},
      typ          = {PUB:(DE-HGF)3 / PUB:(DE-HGF)16},
      pubmed       = {pmid:30779042},
      doi          = {10.1007/978-1-4939-9151-8_15},
      url          = {https://inrepo02.dkfz.de/record/144470},
}