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@ARTICLE{Owen:144535,
author = {R. W. Owen$^*$ and R. Haubner$^*$ and W. Mier$^*$ and A.
Giacosa and W. E. Hull$^*$ and B. Spiegelhalder$^*$ and H.
Bartsch$^*$},
title = {{I}solation, structure elucidation and antioxidant
potential of the major phenolic and flavonoid compounds in
brined olive drupes.},
journal = {Food and chemical toxicology},
volume = {41},
number = {5},
issn = {0278-6915},
address = {New York, NY [u.a.]},
publisher = {Elsevier},
reportid = {DKFZ-2019-01981},
pages = {703-717},
year = {2003},
abstract = {Because olives represent an important component of the
Mediterranean diet, it is necessary to establish unequivocal
identification and quantitation of the major potential
antioxidant phenolic compounds they contain. The major
phenolic antioxidants in two types of brined olives were
isolated and purified by semi-preparative high performance
liquid chromatography. Structural analysis was conducted
using UV spectrophotometry, mass spectrometry and nuclear
magnetic resonance spectroscopy. In particular, completely
assigned 1H and 13C NMR data are presented and errors in
literature data are corrected. The data show that tyrosol,
hydroxytyrosol, 3-(3, 4-dihydroxyphenyl) propanoic acid
(dihydrocaffeic acid), dihydro-p-coumaric acid (phloretic
acid), the phenylpropanoid glucosides acteoside
(verbascoside) and isoacteoside, along with the flavonoids
luteolin and apigenin are major components of the phenolic
fraction of brined black olives. Brined green olives contain
only hydroxytyrosol and traces of other minor phenolics.
Brined olives contain even higher concentrations of phenolic
antioxidants than olive oil and may, therefore, be more
important modulators of cancer chemopreventive activity.},
keywords = {Antioxidants (NLM Chemicals) / Flavonoids (NLM Chemicals) /
Phenols (NLM Chemicals) / Plant Extracts (NLM Chemicals) /
Reactive Oxygen Species (NLM Chemicals)},
cin = {C010},
ddc = {610},
cid = {I:(DE-He78)C010-20160331},
pnm = {313 - Cancer risk factors and prevention (POF3-313)},
pid = {G:(DE-HGF)POF3-313},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:12659724},
url = {https://inrepo02.dkfz.de/record/144535},
}