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@ARTICLE{Edelmann:144616,
      author       = {D. Edelmann$^*$ and M. Hummel$^*$ and T. Hielscher$^*$ and
                      M. Saadati$^*$ and A. Benner$^*$},
      title        = {{M}arginal variable screening for survival endpoints.},
      journal      = {Biometrical journal},
      volume       = {62},
      number       = {3},
      issn         = {1521-4036},
      address      = {Berlin},
      publisher    = {Wiley-VCH},
      reportid     = {DKFZ-2019-02058},
      pages        = {610-626},
      year         = {2020},
      note         = {2020 May;62(3):610-626#EA:C060#LA:C060#},
      abstract     = {When performing survival analysis in very high dimensions,
                      it is often required to reduce the number of covariates
                      using preliminary screening. During the last years, a large
                      number of variable screening methods for the survival
                      context have been developed. However, guidance is missing
                      for choosing an appropriate method in practice. The aim of
                      this work is to provide an overview of marginal variable
                      screening methods for survival and develop recommendations
                      for their use. For this purpose, a literature review is
                      given, offering a comprehensive and structured introduction
                      to the topic. In addition, a novel screening procedure based
                      on distance correlation and martingale residuals is
                      proposed, which is particularly useful in detecting
                      nonmonotone associations. For evaluating the performance of
                      the discussed approaches, a simulation study is conducted,
                      comparing the true positive rates of competing variable
                      screening methods in different settings. A real data example
                      on mantle cell lymphoma is provided.},
      cin          = {C060},
      ddc          = {570},
      cid          = {I:(DE-He78)C060-20160331},
      pnm          = {313 - Cancer risk factors and prevention (POF3-313)},
      pid          = {G:(DE-HGF)POF3-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:31448463},
      doi          = {10.1002/bimj.201800269},
      url          = {https://inrepo02.dkfz.de/record/144616},
}