% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Steindorf:144648,
      author       = {K. Steindorf$^*$ and D. Clauss$^*$ and C. Tjaden and T.
                      Hackert and F. Herbolsheimer$^*$ and T. Bruckner and L.
                      Schneider and C. M. Ulrich and J. Wiskemann},
      title        = {{Q}uality of {L}ife, {F}atigue, and {S}leep {P}roblems in
                      {P}ancreatic {C}ancer {P}atients - {A} {R}andomized {T}rial
                      on the {E}ffects of {E}xercise},
      journal      = {Deutsches Ärzteblatt international},
      volume       = {116},
      number       = {27-28},
      issn         = {1866-0452},
      address      = {Köln},
      publisher    = {Dt. Ärzte-Verl.},
      reportid     = {DKFZ-2019-02090},
      pages        = {471-478},
      year         = {2019},
      note         = {EA:C110},
      abstract     = {Improving quality of life (QoL) is an important treatment
                      goal in pancreatic cancer patients. Although the beneficial
                      effects of exercise on QoL are well understood, few studies
                      have investigated more aggressive cancers such as pancreatic
                      cancer.Within a randomized trial, we assessed the efficacy
                      of 6-month resistance training on physical functioning
                      (primary outcome) and further QoL-related outcomes. 65
                      pancreatic cancer patients were assigned to home-based
                      training, supervised training, or a usual care control
                      group. Analysis-of-covariance models on changes from
                      baseline to 6 and 3 months were ap- plied.47 patients
                      completed the intervention period. After 6 months, no
                      effects of resistance training were observed. However, after
                      3 months, explorative analyses showed significant
                      between-group mean differences (MD) in favor for resistance
                      training for physical functioning (pooled group: MD=11.0;
                      p=0.016; effect size[ES]=0.31), as well as for global QoL
                      (MD=12.1; p=0.016; effect size=0.56), and other outcomes,
                      such as sleep problems and fatigue. Multiple imputation
                      analyses yielded similar results. Home-based and supervised
                      training performed similarly.This first randomized
                      resistance training trial in pancreatic cancer patients
                      indicated clinically relevant improve- ments in QoL after 3
                      but not after 6 months. Given the severity of pancreatic
                      cancer, exercise recommendations may already commence at
                      surgery.},
      cin          = {C110},
      ddc          = {610},
      cid          = {I:(DE-He78)C110-20160331},
      pnm          = {313 - Cancer risk factors and prevention (POF3-313)},
      pid          = {G:(DE-HGF)POF3-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:31431236},
      doi          = {10.3238/arztebl.2019.0471},
      url          = {https://inrepo02.dkfz.de/record/144648},
}