%0 Journal Article
%A Peng, Le
%A Balavarca, Yesilda
%A Weigl, Korbinian
%A Hoffmeister, Michael
%A Brenner, Hermann
%T Head-to-Head Comparison of the Performance of 17 Risk Models for Predicting Presence of Advanced Neoplasms in Colorectal Cancer Screening.
%J The American journal of gastroenterology
%V 114
%N 9
%@ 0002-9270
%C London [u.a.]
%I Nature
%M DKFZ-2019-02141
%P 1520-1530
%D 2019
%X Many risk scores have been proposed to predict presence of advanced colorectal neoplasms, but a comprehensive comparison conducted in the same population is sparse. The aim of this study was to evaluate and directly compare the diagnostic performance of published risk prediction models for advanced colorectal neoplasms.Data were drawn from 2 cohorts of subjects undergoing screening colonoscopy in Germany, i.e., KolosSal (n = 16,195) and BliTz (n = 7,444). Absolute risks and relative risks were generated for the presence of at least 1 advanced neoplasm, taking the lowest risk group as the reference group. Performance of risk models was assessed by the area under the receiver operating characteristic curve (AUC) and compared by the net reclassification improvement.The 2 cohorts included 1,917 (11.8
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:31464746
%R 10.14309/ajg.0000000000000370
%U https://inrepo02.dkfz.de/record/144699