MU05
DKTK MU Translationale Krebsforschung
| ID | I:(DE-He78)MU05-20160331 |
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Journal Article
Murr, J. ; Schneider, C. ; Duan, N. ; Köse, H. ; Rajamani, A. ; He, X. ; Buchloh, J. ; Hintze, C. ; Naik, A. ; Goeke, D. ; Rjasanow, N. ; Krauß, L. ; Nguyen, A. ; Widholz, S. A. ; Schneeweis, C. ; Trozzo, R. ; Orben, F. ; Mueller, S. ; Öllinger, R. ; Montero, J. J. ; Dudek, M. ; Knolle, P. ; Kong, B. ; Ellenrieder, V. ; Contreras, C. T. ; Hessmann, E. ; Grade, M. ; Ghadimi, M. ; Braun, C. J. ; Rad, R.DKFZ* ; Reichert, M.DKFZ* ; Keller, U.DKFZ* ; Schmid, R. M. ; Boutz, P. L. ; Saur, D.DKFZ* ; Wirth, M.DKFZ* ; Krämer, O. H. ; Schneider, G.
The Protein Phosphatase Inhibitor LB100 Targets the Mesenchymal Lineage of Pancreatic Ductal Adenocarcinoma
MedComm 7(6), e70794 (2026) [10.1002/mco2.70794]2026
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Journal Article
Belz, L. ; van den Heuvel, D. ; Kilani, B. ; Martinez-Navarro, A. ; Akhalkatsi, A. ; Joppich, M. ; Zhu, Y. ; Ding, Q. ; Wan, J. ; Stermann, J. ; Winterhalter, J. ; Messerer, D. ; Titova, A. ; Balaji, S. ; Giri, S. ; Eivers, L. ; Widholz, S.DKFZ* ; Bärthel, S.DKFZ* ; Raatz, E. ; Saur, D.DKFZ* ; Lauber, K. ; Beyer, G. ; Mayerle, J. ; Ormanns, S. ; Guenther, M. ; Massberg, S. ; Ishikawa-Ankerhold, H. ; Stark, K.
Neutrophil-Driven Trogocytosis in PDAC Liver Metastases Restrains Immunosuppressive Macrophage Polarization and Limits Metastatic Progression.
Gastroenterology nn, nn (2026) [10.1053/j.gastro.2026.04.021]2026
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Journal Article (Review Article)
Roth, S. ; Apte, M. ; Balachandran, V. P. ; Biffi, G. ; Conroy, T. ; Cukierman, E. ; Dotan, E. ; Esposito, I. ; Grünwald, B. T. ; Klauß, M. ; Klein, A. P. ; Malats, N. ; O Reilly, E. M. ; Pishvaian, M. J. ; Real, F. X. ; Saur, D. K. M.DKFZ* ; Siveke, J.DKFZ* ; Michalski, C. W.
Pancreatic cancer.
Nature reviews / Disease Primers 12(1), 23 (2026) [10.1038/s41572-026-00699-6]2026
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Journal Article
Spielmann, V. ; Buchloh, J. ; Selcen, S. ; Schneider, C. ; Jansari, S. ; Fang, X. ; Duan, N. ; Demirdizen, E. ; Krauß, L. ; Eggert, J. ; Siegfried, G. ; Fedou, S. ; Lenz, C. ; Wieland, L. ; Conradi, L.-C. ; Reichert, M.DKFZ* ; Ellenrieder, V. ; Ghadimi, M. ; Grade, M. ; Hessmann, E. ; Khatib, A.-M. ; Braun, C. J. ; Wegwitz, F. ; Saur, D. K. M.DKFZ* ; Wirth, M.DKFZ* ; Schneider, G.
Targeting PRMT5 Inhibitor-Induced Adaptation in Pancreatic Cancer with the RBM39 Degrader Indisulam.
Cancer research communications 6(9), 2039 - 2055 (2026) [10.1158/2767-9764.CRC-25-0670]2026
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Journal Article
Mota Reyes, C.DKFZ* ; Goetz, M. R. ; Algül, H. ; Dogruoez, A. ; Falcomatà, C. ; Gaida, M. M. ; Görgülü, K. ; Gültekin, Y. ; Gürcinar, I. H. ; Hasselluhn, M. C. ; Istvanffy, R. ; Kalluri, R. ; Kalluri, V. S. ; Kiemen, A. ; Kim, P. ; Lee, S.-W. ; Lesina, M. ; Yu, P. ; Maitra, A. ; Müller, C. M. ; Müller, S. ; Nam, D. ; Olive, K. P. ; Pasca Di Magliano, M. ; Rad, R.DKFZ* ; Saur, D. K. M.DKFZ* ; Vander Heiden, M. G. ; Vormehr, M. ; Wood, L. D. ; Yöndem, E. ; Zschäpitz, D. ; Karakas, D. ; Friess, H. ; Ceyhan, G. O. ; Club, E. P. (Collaboration Author) ; Demir, I. E.
Pancreatic ductal adenocarcinoma: The Vision of Heracles.
Cancer cell 44(9), 1721 - 1726 (2026) [10.1016/j.ccell.2026.07.014]2026
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Journal Article
Mueller, S. ; de Andrade Krätzig, N. ; Tschurtschenthaler, M.DKFZ* ; et al
A disease model resource reveals core principles of tissue-specific cancer evolution.
Nature 653, 265–276 (2026) [10.1038/s41586-026-10187-2]2026
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Journal Article
Jesinghaus, M. ; Silva, M. G. ; Zaurito, A. E. ; Brunner, V. ; Saab, F.DKFZ* ; Rajamani, A. ; de Andrade Krätzig, N. ; Bodenstein, N. ; Guillemant, R. ; Pohl, J. ; Schmitt, M. ; Öllinger, R. ; Fusco, F. ; Shakhtour, J. ; Klare, P. ; Janssen, K.-P. ; Foersch, S. ; Steiger, K. ; Rad, R.DKFZ* ; Pfarr, N. ; Saur, D.DKFZ* ; Tschurtschenthaler, M.DKFZ*
A translational colorectal cancer organoid biobank mirrors patients' tumor histology, molecular profiles, and treatment responses.
Journal of experimental & clinical cancer research 45(1), 89 (2026) [10.1186/s13046-026-03666-x]2026
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Journal Article
Frädrich, J. ; Reyes, C. M.DKFZ* ; Hendel, M. ; Brunner, V. ; Toledo, B. ; Manevski, D. ; Sommer, A. ; Häußler, D. ; Beck, D. ; Lucarelli, D. ; Martínez de Villareal, J. ; Halle, L. ; Kfuri-Rubens, R. ; Çifcibaşı, K. ; Hirschberger, A. ; Öllinger, R. ; Knolle, P. A. ; Steiger, K. ; Rad, R. ; Theis, F. J. ; Real, F. X. ; Bärthel, S.DKFZ* ; Böttcher, J. P. ; Saur, D.DKFZ* ; Demir, I. E.DKFZ* ; Krüger, A.
Multimodal profiling of pancreatic cancer reveals a TIMP-1-dominated secretory profile determining pro-tumor immunoinstruction in human cancers.
Cell reports / Medicine 7(1), 102546 (2026) [10.1016/j.xcrm.2025.102546]2026
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Journal Article
Hachani, K. ; Yazdi, M. ; Carcopino, C. ; Khademi Moghadam, F. ; Smith, M. D. ; Trill, A. ; Trefny, M. P. ; Hasanzadeh Kafshgari, M. ; Hoch, C. C. ; Gaballa, A.DKFZ* ; Alkotub, B. ; Altomonte, J. ; Pockley, A. G. ; Wagner, E. ; Wollenberg, B. ; Kobold, S.DKFZ* ; Multhoff, G. ; Bashiri Dezfouli, A.
Development of CAR NK Cell Lines Selectively Targeting Cancer Cells Expressing Membrane Hsp70.
MedComm 7(5), e70753 (2026) [10.1002/mco2.70753]2026
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Journal Article
Hirsch, N.-D. ; Perl, M. ; Holzinger, S. ; Barz, C. ; Enßle, S. ; Johannes, W. ; Conrad, A. ; Unterholzner, J. J. ; Obermeier, V. ; Tschurtschenthaler, M.DKFZ* ; Johannes, L. ; Janssen, K.-P.
The Gb3-synthase A4GALT is an epigenetically regulated driver of tumor invasiveness in gastrointestinal cancer.
BMC cancer 26, 274 (2026) [10.1186/s12885-026-15600-7]2026
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All known publications ...
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