W192
Single-cell Open Lab
Also known as:W192 scOpen Lab
| ID | I:(DE-He78)W192-20160331 |
Recent Publications
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Journal Article
Staehle, H. F. ; Koellerer, C. ; Staehle, A. M. ; Schulze, J. ; Eble, P. ; Müller, A. ; Zell, F. ; Müller, J. M. ; Perner, F. ; Attia, A. ; Mallm, J.-P.DKFZ* ; Pozdnyakova, O. ; Rippe, K.DKFZ* ; Brors, B.DKFZ* ; Feuerbach, L.DKFZ* ; Imbusch, C. D.DKFZ* ; Metzger, E. ; Schüle, R. ; Pahl, H. L. ; Jutzi, J. S.
Lysine-specific demethylase 1 regulates hematopoietic stem cell expansion and myeloid cell differentiation.
Cell death & disease 16(1), 619 (2025) [10.1038/s41419-025-07951-z]2025
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Okonechnikov, K. (First author)DKFZ* ; Joshi, P. K. (First author)DKFZ* ; Körber, V. (First author)DKFZ* ; Rademacher, A.DKFZ* ; Bortolomeazzi, M.DKFZ* ; Mallm, J.-P.DKFZ* ; Vaillant, J.DKFZ* ; da Silva, P. B. G.DKFZ* ; Statz, B.DKFZ* ; Sepp, M. ; Sarropoulos, I. ; Yamada, T. ; Wittmann, A.DKFZ* ; Schramm, K.DKFZ* ; Blattner-Johnson, M.DKFZ* ; Fiesel, P.DKFZ* ; Jones, B.DKFZ* ; Jäger, N.DKFZ* ; Milde, T.DKFZ* ; Pajtler, K.DKFZ* ; van Tilburg, C. M.DKFZ* ; Witt, O.DKFZ* ; Bochennek, K. ; Weber, K. J.DKFZ* ; Nonnenmacher, L. ; Reimann, C. ; Ghasemi, D. R.DKFZ* ; Schüller, U. ; Mynarek, M. ; Rutkowski, S. ; Jones, D.DKFZ* ; Korshunov, A.DKFZ* ; Rippe, K.DKFZ* ; Westermann, F.DKFZ* ; Thongjuea, S.DKFZ* ; Höfer, T.DKFZ* ; Kaessmann, H.DKFZ* ; Kutscher, L. (Last author)DKFZ* ; Pfister, S. (Last author)DKFZ*
Oncogene aberrations drive medulloblastoma progression, not initiation.
Nature 642(8069), 1062-1072 (2025) [10.1038/s41586-025-08973-5]2025
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Journal Article
Ernst, K. (First author)DKFZ* ; Okonechnikov, K. (First author)DKFZ* ; Bageritz, J.DKFZ* ; Perera, A. A.DKFZ* ; Mallm, J.-P.DKFZ* ; Wittmann, A.DKFZ* ; Maaß, K. K.DKFZ* ; Leible, S.DKFZ* ; Boutros, M.DKFZ* ; Pfister, S. M.DKFZ* ; Zuckermann, M. (Last author)DKFZ* ; Jones, D. (Last author)DKFZ*
A simplified preparation method for single-nucleus RNA-sequencing using long-term frozen brain tumor tissues.
Scientific reports 15(1), 12849 (2025) [10.1038/s41598-025-97053-9]2025
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Journal Article
Seufert, I. (First author)DKFZ* ; Gerosa, I.DKFZ* ; Varamogianni-Mamatsi, V. ; Vladimirova, A.DKFZ* ; Sen, E.DKFZ* ; Mantz, S.DKFZ* ; Rademacher, A.DKFZ* ; Schumacher, S.DKFZ* ; Liakopoulos, P. ; Kolovos, P. ; Anders, S. ; Mallm, J.-P.DKFZ* ; Papantonis, A. ; Rippe, K. (Last author)DKFZ*
Two distinct chromatin modules regulate proinflammatory gene expression.
Nature cell biology nn, nn (2025) [10.1038/s41556-025-01819-2]2025
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Journal Article (Review Article)
Hartmann, M. (First author)DKFZ* ; Schönung, M. (First author)DKFZ* ; Rajak, J. ; Maurer, V.DKFZ* ; Hai, L.DKFZ* ; Bauer, K.DKFZ* ; Hakobyan, M.DKFZ* ; Stäble, S.DKFZ* ; Langstein, J.DKFZ* ; Jardine, L. ; Roelz, R. ; Bohler, S. ; Khabirova, E. ; Maag, A.-H. ; Vonficht, D.DKFZ* ; Lebrecht, D. ; Bernt, K. M. ; Tan, K. ; Chen, C. ; Alikarami, F. ; Meyer, J. ; Wang, J. ; Boch, T. ; Flore, N. V.DKFZ* ; Lutsik, P.DKFZ* ; Milsom, M.DKFZ* ; Raffel, S. ; Buske, C. ; Haas, S. ; Haniffa, M. ; Mallm, J.-P.DKFZ* ; Behjati, S. ; Bonder, M. J.DKFZ* ; Fröhling, S.DKFZ* ; Stieglitz, E. ; Niemeyer, C. M. ; Hey, J. (Last author)DKFZ* ; Flotho, C.DKFZ* ; Plass, C. (Last author)DKFZ* ; Erlacher, M.DKFZ* ; Schlesner, M. (Last author)DKFZ* ; Lipka, D. (Last author)DKFZ*
Molecular Plasticity Results in Oncofetal Reprogramming and Therapeutic Vulnerabilities in Juvenile Myelomonocytic Leukemia.
Blood cancer discovery nn, nn (2025) [10.1158/2643-3230.BCD-25-0246]2025
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Journal Article
Baumhardt, T. M. ; Amoah, A. ; Hoenicka, M. ; Liebold, A. ; Sakk, V. ; Soller, K. ; Vollmer, A. ; Kull, M. ; Kronke, J. ; Mallm, J.-P.DKFZ* ; Geiger, H. ; Mulaw, M.
Functional and molecular analyses reveal impaired HSPCs in Multiple Myeloma patients post-induction.
Stem cells translational medicine 14(11), szaf061 (2025) [10.1093/stcltm/szaf061]2025
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Journal Article
Rademacher, A. (First author)DKFZ* ; Huseynov, A. (First author)DKFZ* ; Bortolomeazzi, M. (First author)DKFZ* ; Wille, S. J.DKFZ* ; Schumacher, S.DKFZ* ; Sant, P.DKFZ* ; Keitel, D.DKFZ* ; Okonechnikov, K.DKFZ* ; Ghasemi, D. R.DKFZ* ; Pajtler, K. W.DKFZ* ; Mallm, J.-P.DKFZ* ; Rippe, K. (Last author)DKFZ*
Comparison of spatial transcriptomics technologies using tumor cryosections.
Genome biology 26(1), 176 (2025) [10.1186/s13059-025-03624-4]2025
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Journal Article
Thiel, V. (First author)DKFZ* ; Renders, S. (First author)DKFZ* ; Panten, J. (First author)DKFZ* ; Dross, N. ; Bauer, K.DKFZ* ; Azorin, D.DKFZ* ; Henriques, V. ; Vogel, V. ; Klein, C.DKFZ* ; Leppä, A.-M.DKFZ* ; Barriuso Ortega, I.DKFZ* ; Schwickert, J.DKFZ* ; Ourailidis, I. ; Mochayedi, J. ; Mallm, J.-P.DKFZ* ; Müller-Tidow, C. ; Monyer, H.DKFZ* ; Neoptolemos, J. ; Hackert, T. ; Stegle, O.DKFZ* ; Odom, D.DKFZ* ; Offringa, R.DKFZ* ; Stenzinger, A. ; Winkler, F.DKFZ* ; Sprick, M.DKFZ* ; Trumpp, A. (Last author)DKFZ*
Characterization of single neurons reprogrammed by pancreatic cancer.
Nature 640, 1042–1051 (2025) [10.1038/s41586-025-08735-3]2025
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Journal Article
Lutz, R. (First author)DKFZ* ; Poos, A. (First author)DKFZ* ; Solé-Boldo, L. ; John, L. (First author)DKFZ* ; Wagner, J.DKFZ* ; Prokoph, N.DKFZ* ; Baertsch, M. A.DKFZ* ; Vonficht, D.DKFZ* ; Palit, S. ; Brobeil, A. ; Mechtersheimer, G. ; Hildenbrand, N. ; Hemmer, S. ; Steiger, S.DKFZ* ; Horn, S. ; Pepke, W. ; Spranz, D. M. ; Rehnitz, C. ; Sant, P.DKFZ* ; Mallm, J.-P.DKFZ* ; Friedrich, M. J. ; Reichert, P. ; Huhn, S. ; Trumpp, A.DKFZ* ; Rippe, K.DKFZ* ; Haghverdi, L. ; Fröhling, S.DKFZ* ; Müller-Tidow, C. ; Hübschmann, D.DKFZ* ; Goldschmidt, H. ; Willimsky, G.DKFZ* ; Sauer, S. ; Raab, M. S.DKFZ* ; Haas, S.DKFZ* ; Weinhold, N. (Last author)DKFZ*
Bone marrow breakout lesions act as key sites for tumor-immune cell diversification in multiple myeloma.
Science immunology 10(104), eadp6667 (2025) [10.1126/sciimmunol.adp6667]2025
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Journal Article (Erratum/Correction)
Smirnov, P. (First author)DKFZ* ; Przybilla, M. J. (First author)DKFZ* ; Simovic-Lorenz, M. (First author)DKFZ* ; Parra, R. G. (First author)DKFZ* ; Susak, H. (First author)DKFZ* ; Aichmüller-Ratnaparkhe, M.DKFZ* ; Wong, J. K.DKFZ* ; Körber, V.DKFZ* ; Mallm, J.-P.DKFZ* ; Philippos, G.DKFZ* ; Sill, M.DKFZ* ; Kolb, T.DKFZ* ; Kumar, R.DKFZ* ; Casiraghi, N.DKFZ* ; Okonechnikov, K.DKFZ* ; Ghasemi, D. R.DKFZ* ; Maaß, K. K.DKFZ* ; Pajtler, K.DKFZ* ; Jauch, A. ; Korshunov, A.DKFZ* ; Höfer, T.DKFZ* ; Zapatka, M.DKFZ* ; Pfister, S.DKFZ* ; Huber, W.DKFZ* ; Stegle, O. (Last author)DKFZ* ; Ernst, A. (Last author)DKFZ*
Author Correction: Multi-omic and single-cell profiling of chromothriptic medulloblastoma reveals genomic and transcriptomic consequences of genome instability.
Nature Communications 16(1), 1085 (2025) [10.1038/s41467-025-56164-7]2025
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All known publications ...
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