W192
Single-cell Open Lab
Also known as:W192 scOpen Lab
ID | I:(DE-He78)W192-20160331 |
Recent Publications
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Journal Article
Staehle, H. F. ; Koellerer, C. ; Staehle, A. M. ; Schulze, J. ; Eble, P. ; Müller, A. ; Zell, F. ; Müller, J. M. ; Perner, F. ; Attia, A. ; Mallm, J.-P.DKFZ* ; Pozdnyakova, O. ; Rippe, K.DKFZ* ; Brors, B.DKFZ* ; Feuerbach, L.DKFZ* ; Imbusch, C. D.DKFZ* ; Metzger, E. ; Schüle, R. ; Pahl, H. L. ; Jutzi, J. S.
Lysine-specific demethylase 1 regulates hematopoietic stem cell expansion and myeloid cell differentiation.
Cell death & disease 16(1), 619 (2025) [10.1038/s41419-025-07951-z]2025
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Journal Article
Okonechnikov, K. (First author)DKFZ* ; Joshi, P. K. (First author)DKFZ* ; Körber, V. (First author)DKFZ* ; Rademacher, A.DKFZ* ; Bortolomeazzi, M.DKFZ* ; Mallm, J.-P.DKFZ* ; Vaillant, J.DKFZ* ; da Silva, P. B. G.DKFZ* ; Statz, B.DKFZ* ; Sepp, M. ; Sarropoulos, I. ; Yamada, T. ; Wittmann, A.DKFZ* ; Schramm, K.DKFZ* ; Blattner-Johnson, M.DKFZ* ; Fiesel, P.DKFZ* ; Jones, B.DKFZ* ; Jäger, N.DKFZ* ; Milde, T.DKFZ* ; Pajtler, K.DKFZ* ; van Tilburg, C. M.DKFZ* ; Witt, O.DKFZ* ; Bochennek, K. ; Weber, K. J.DKFZ* ; Nonnenmacher, L. ; Reimann, C. ; Ghasemi, D. R.DKFZ* ; Schüller, U. ; Mynarek, M. ; Rutkowski, S. ; Jones, D.DKFZ* ; Korshunov, A.DKFZ* ; Rippe, K.DKFZ* ; Westermann, F.DKFZ* ; Thongjuea, S.DKFZ* ; Höfer, T.DKFZ* ; Kaessmann, H.DKFZ* ; Kutscher, L. (Last author)DKFZ* ; Pfister, S. (Last author)DKFZ*
Oncogene aberrations drive medulloblastoma progression, not initiation.
Nature 642(8069), 1062-1072 (2025) [10.1038/s41586-025-08973-5]2025
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Journal Article
Ernst, K. (First author)DKFZ* ; Okonechnikov, K. (First author)DKFZ* ; Bageritz, J.DKFZ* ; Perera, A. A.DKFZ* ; Mallm, J.-P.DKFZ* ; Wittmann, A.DKFZ* ; Maaß, K. K.DKFZ* ; Leible, S.DKFZ* ; Boutros, M.DKFZ* ; Pfister, S. M.DKFZ* ; Zuckermann, M. (Last author)DKFZ* ; Jones, D. (Last author)DKFZ*
A simplified preparation method for single-nucleus RNA-sequencing using long-term frozen brain tumor tissues.
Scientific reports 15(1), 12849 (2025) [10.1038/s41598-025-97053-9]2025
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Journal Article
Rademacher, A. (First author)DKFZ* ; Huseynov, A. (First author)DKFZ* ; Bortolomeazzi, M. (First author)DKFZ* ; Wille, S. J.DKFZ* ; Schumacher, S.DKFZ* ; Sant, P.DKFZ* ; Keitel, D.DKFZ* ; Okonechnikov, K.DKFZ* ; Ghasemi, D. R.DKFZ* ; Pajtler, K. W.DKFZ* ; Mallm, J.-P.DKFZ* ; Rippe, K. (Last author)DKFZ*
Comparison of spatial transcriptomics technologies using tumor cryosections.
Genome biology 26(1), 176 (2025) [10.1186/s13059-025-03624-4]2025
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Journal Article
Thiel, V. (First author)DKFZ* ; Renders, S. (First author)DKFZ* ; Panten, J. (First author)DKFZ* ; Dross, N. ; Bauer, K.DKFZ* ; Azorin, D.DKFZ* ; Henriques, V. ; Vogel, V. ; Klein, C.DKFZ* ; Leppä, A.-M.DKFZ* ; Barriuso Ortega, I.DKFZ* ; Schwickert, J.DKFZ* ; Ourailidis, I. ; Mochayedi, J. ; Mallm, J.-P.DKFZ* ; Müller-Tidow, C. ; Monyer, H.DKFZ* ; Neoptolemos, J. ; Hackert, T. ; Stegle, O.DKFZ* ; Odom, D.DKFZ* ; Offringa, R.DKFZ* ; Stenzinger, A. ; Winkler, F.DKFZ* ; Sprick, M.DKFZ* ; Trumpp, A. (Last author)DKFZ*
Characterization of single neurons reprogrammed by pancreatic cancer.
Nature 640, 1042–1051 (2025) [10.1038/s41586-025-08735-3]2025
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Journal Article
Lutz, R. (First author)DKFZ* ; Poos, A. (First author)DKFZ* ; Solé-Boldo, L. ; John, L. (First author)DKFZ* ; Wagner, J.DKFZ* ; Prokoph, N.DKFZ* ; Baertsch, M. A.DKFZ* ; Vonficht, D.DKFZ* ; Palit, S. ; Brobeil, A. ; Mechtersheimer, G. ; Hildenbrand, N. ; Hemmer, S. ; Steiger, S.DKFZ* ; Horn, S. ; Pepke, W. ; Spranz, D. M. ; Rehnitz, C. ; Sant, P.DKFZ* ; Mallm, J.-P.DKFZ* ; Friedrich, M. J. ; Reichert, P. ; Huhn, S. ; Trumpp, A.DKFZ* ; Rippe, K.DKFZ* ; Haghverdi, L. ; Fröhling, S.DKFZ* ; Müller-Tidow, C. ; Hübschmann, D.DKFZ* ; Goldschmidt, H. ; Willimsky, G.DKFZ* ; Sauer, S. ; Raab, M. S.DKFZ* ; Haas, S.DKFZ* ; Weinhold, N. (Last author)DKFZ*
Bone marrow breakout lesions act as key sites for tumor-immune cell diversification in multiple myeloma.
Science immunology 10(104), eadp6667 (2025) [10.1126/sciimmunol.adp6667]2025
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Journal Article (Erratum/Correction)
Smirnov, P. (First author)DKFZ* ; Przybilla, M. J. (First author)DKFZ* ; Simovic-Lorenz, M. (First author)DKFZ* ; Parra, R. G. (First author)DKFZ* ; Susak, H. (First author)DKFZ* ; Aichmüller-Ratnaparkhe, M.DKFZ* ; Wong, J. K.DKFZ* ; Körber, V.DKFZ* ; Mallm, J.-P.DKFZ* ; Philippos, G.DKFZ* ; Sill, M.DKFZ* ; Kolb, T.DKFZ* ; Kumar, R.DKFZ* ; Casiraghi, N.DKFZ* ; Okonechnikov, K.DKFZ* ; Ghasemi, D. R.DKFZ* ; Maaß, K. K.DKFZ* ; Pajtler, K.DKFZ* ; Jauch, A. ; Korshunov, A.DKFZ* ; Höfer, T.DKFZ* ; Zapatka, M.DKFZ* ; Pfister, S.DKFZ* ; Huber, W.DKFZ* ; Stegle, O. (Last author)DKFZ* ; Ernst, A. (Last author)DKFZ*
Author Correction: Multi-omic and single-cell profiling of chromothriptic medulloblastoma reveals genomic and transcriptomic consequences of genome instability.
Nature Communications 16(1), 1085 (2025) [10.1038/s41467-025-56164-7]2025
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Journal Article
Jannasch, A. ; Tulok, S. ; Okafornta, C. W. ; Kugel, T. ; Bortolomeazzi, M.DKFZ* ; Boissonnet, T. ; Schmidt, C.DKFZ* ; Vogelsang, A. ; Dittfeld, C. ; Tugtekin, S.-M. ; Matschke, K. ; Paliulis, L. ; Thomas, C. ; Lindemann, D. ; Fabig, G. ; Müller-Reichert, T.
Setting up an institutional OMERO environment for bioimage data: Perspectives from both facility staff and users.
Journal of microscopy 297(1), 105-119 (2025) [10.1111/jmi.13360]2025
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Preprint
Joshi, P. K. (First author)DKFZ* ; Stelzer, T.DKFZ* ; Okonechnikov, K.DKFZ* ; Sarropoulos, I. ; Sepp, M. ; Pour-Jamnani, M. V.DKFZ* ; Rademacher, A.DKFZ* ; Yamada-Saito, T. ; Schneider, C. ; Schmidt, J. ; Schäfer, P. ; Leiss, K. ; Bortolomeazzi, M.DKFZ* ; Mallm, J.-P.DKFZ* ; da Silva, P. B. G.DKFZ* ; Statz, B.DKFZ* ; Wittmann, A.DKFZ* ; Schramm, K.DKFZ* ; Blattner-Johnson, M.DKFZ* ; Fiesel, P.DKFZ* ; Jones, B.DKFZ* ; Milde, T.DKFZ* ; Pajtler, K.DKFZ* ; van Tilburg, C. M.DKFZ* ; Witt, O.DKFZ* ; Rippe, K.DKFZ* ; Korshunov, A.DKFZ* ; Jones, D. T. W.DKFZ* ; Hovestadt, V. ; Northcott, P. A. ; Thongjuea, S.DKFZ* ; Jäger, N.DKFZ* ; Kaessmann, H. ; Pfister, S. M.DKFZ* ; Kutscher, L. (Last author)DKFZ*
Gene regulatory network landscape of Group 3/4 medulloblastoma
[doi.org/10.1101/2024.02.09.579680]
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Preprint
Okonechnikov, K. (First author)DKFZ* ; Joshi, P. K.DKFZ* ; Körber, V.DKFZ* ; Rademacher, A.DKFZ* ; Bortolomeazzi, M.DKFZ* ; Mallm, J.-P.DKFZ* ; da Silva, P. B. G.DKFZ* ; Statz, B.DKFZ* ; Sepp, M. ; Sarropoulos, I. ; Yamada-Saito, T. ; Vaillant, J.DKFZ* ; Wittmann, A.DKFZ* ; Schramm, K.DKFZ* ; Blattner-Johnson, M.DKFZ* ; Fiesel, P.DKFZ* ; Jones, B.DKFZ* ; Milde, T.DKFZ* ; Pajtler, K.DKFZ* ; van Tilburg, C. M.DKFZ* ; Witt, O.DKFZ* ; Bochennek, K. ; Weber, K. J. ; Nonnenmacher, L. ; Reimann, C. ; Schüller, U. ; Mynarek, M. ; Rutkowski, S. ; Jones, D. T. W.DKFZ* ; Korshunov, A.DKFZ* ; Rippe, K.DKFZ* ; Westermann, F.DKFZ* ; Thongjuea, S.DKFZ* ; Höfer, T.DKFZ* ; Kaessmann, H. ; Kutscher, L.DKFZ* ; Pfister, S. (Last author)DKFZ*
Medulloblastoma oncogene aberrations are not involved in tumor initiation, but essential for disease progression and therapy resistance
[doi.org/10.1101/2024.02.09.579690]
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All known publications ...
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