TY  - JOUR
AU  - Gao, Xin
AU  - Xuan, Yang
AU  - Benner, Axel
AU  - Anusruti, Ankita
AU  - Brenner, Hermann
AU  - Schöttker, Ben
TI  - Nitric Oxide Metabolites and Lung Cancer Incidence: A Matched Case-Control Study Nested in the ESTHER Cohort.
JO  - Oxidative medicine and cellular longevity
VL  - 2019
SN  - 1942-0994
CY  - Austin, Tex.
PB  - Landes Bioscience
M1  - DKFZ-2019-02324
SP  - 6470950
PY  - 2019
AB  - Studies suggest that nitric oxide (NO) may have a possible role in lung carcinogenesis. This study is aimed to evaluate the association of the NO metabolites, namely, nitrite and nitrate, with lung cancer incidence. We conducted a matched case-control study (n = 245 incident lung cancer cases and n = 735 controls) based on the German ESTHER cohort (n = 9,940). Controls were matched to cases on age, sex, smoking status (never/former/current smoking), and pack-years of smoking. The sum of nitrite and nitrate was measured in urine samples using a colorimetric assay and was standardized for renal function by urinary creatinine. Conditional logistic regression models, adjusted for lifestyle factors, asthma prevalence, and family history of lung cancer, were used to estimate odds ratios (ORs) and 95
LB  - PUB:(DE-HGF)16
C6  - pmid:31565153
C2  - pmc:PMC6745103
DO  - DOI:10.1155/2019/6470950
UR  - https://inrepo02.dkfz.de/record/147188
ER  -