%0 Journal Article
%A Hu, Chunyun
%A Schöttker, Ben
%A Venisse, Nicolas
%A Limousi, Frédérike
%A Saulnier, Pierre Jean
%A Albouy-Llaty, Marion
%A Dupuis, Antoine
%A Brenner, Hermann
%A Migeot, Virginie
%A Hadjadj, Samy
%T Bisphenol A, Chlorinated Derivatives of Bisphenol A and Occurrence of Myocardial Infarction in Patients with Type 2 Diabetes: Nested Case-Control Studies in Two European Cohorts.
%J Environmental science & technology
%V 53
%N 16
%@ 1520-5851
%C Columbus, Ohio
%I American Chemical Society
%M DKFZ-2019-02330
%P 9876 - 9883
%D 2019
%X A positive association between Bisphenol A (BPA) exposure and coronary heart disease has been shown, but not in patients with type 2 diabetes (T2D). During the treatment of drinking water, chlorination leads to the formation of chlorinated derivatives of Bisphenol A (ClxBPA), that have higher estrogenic activity than BPA. No evidence exists for a relationship between exposure to ClxBPA and myocardial infarction in patients with T2D. The objective of this study was to evaluate the relationship between exposure to BPA, ClxBPA and the occurrence of myocardial infarction (MI) in patients with T2D. Two nested case-control studies in two independent European cohorts were performed. Each case with incident MI during follow-up was matched to one control on age, sex, and personal cardiovascular history in the same cohort. Association between baseline urine concentrations of BPA and of ClxBPA and incident MI was determined. Exposure to BPA was 31
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:31310111
%R 10.1021/acs.est.9b02963
%U https://inrepo02.dkfz.de/record/147204