TY  - JOUR
AU  - Hu, Chunyun
AU  - Schöttker, Ben
AU  - Venisse, Nicolas
AU  - Limousi, Frédérike
AU  - Saulnier, Pierre Jean
AU  - Albouy-Llaty, Marion
AU  - Dupuis, Antoine
AU  - Brenner, Hermann
AU  - Migeot, Virginie
AU  - Hadjadj, Samy
TI  - Bisphenol A, Chlorinated Derivatives of Bisphenol A and Occurrence of Myocardial Infarction in Patients with Type 2 Diabetes: Nested Case-Control Studies in Two European Cohorts.
JO  - Environmental science & technology
VL  - 53
IS  - 16
SN  - 1520-5851
CY  - Columbus, Ohio
PB  - American Chemical Society
M1  - DKFZ-2019-02330
SP  - 9876 - 9883
PY  - 2019
AB  - A positive association between Bisphenol A (BPA) exposure and coronary heart disease has been shown, but not in patients with type 2 diabetes (T2D). During the treatment of drinking water, chlorination leads to the formation of chlorinated derivatives of Bisphenol A (ClxBPA), that have higher estrogenic activity than BPA. No evidence exists for a relationship between exposure to ClxBPA and myocardial infarction in patients with T2D. The objective of this study was to evaluate the relationship between exposure to BPA, ClxBPA and the occurrence of myocardial infarction (MI) in patients with T2D. Two nested case-control studies in two independent European cohorts were performed. Each case with incident MI during follow-up was matched to one control on age, sex, and personal cardiovascular history in the same cohort. Association between baseline urine concentrations of BPA and of ClxBPA and incident MI was determined. Exposure to BPA was 31
LB  - PUB:(DE-HGF)16
C6  - pmid:31310111
DO  - DOI:10.1021/acs.est.9b02963
UR  - https://inrepo02.dkfz.de/record/147204
ER  -