%0 Journal Article
%A Schwarz, Daniel
%A Niederle, Thomas
%A Münch, Philipp
%A Hielscher, Thomas
%A Hassel, Jessica C
%A Schlemmer, Heinz-Peter
%A Platten, Michael
%A Winkler, Frank
%A Wick, Wolfgang
%A Heiland, Sabine
%A Delorme, Stefan
%A Bendszus, Martin
%A Bäumer, Philipp
%A Breckwoldt, Michael
%T Susceptibility-weighted imaging in malignant melanoma brain metastasis.
%J Journal of magnetic resonance imaging
%V 50
%N 4
%@ 1522-2586
%C New York, NY
%I Wiley-Liss
%M DKFZ-2019-02343
%P 1251 - 1259
%D 2019
%X The value of cerebral susceptibility-weighted imaging (SWI) in malignant melanoma (MM) patients remains controversial and the effect of melanin on SWI is not well understood.To systematically analyze the spectrum of intracerebral findings in MM brain metastases (BM) on SWI and to determine the diagnostic value of SWI.Retrospective.In all, 100 patients with melanoma BM (69 having received radiotherapy [RT] and 31 RT-naïve) and a control group of 100 melanoma patients without BM were included. For detailed analysis of signal characteristics, 175 metastases were studied.Gradient echo SWI sequence at 1.5, 3.0, and 9.4 T.Signal characteristics from melanotic and amelanotic BMs on SWI with a focus on blooming artifacts were analyzed, as well as the presence and longitudinal dynamics of isolated SWI blooming artifacts in patients with and without BM.Chi-squared and Student's t-test were used for contingency table measures and group data of signal and clinical characteristics, respectively.Melanotic and amelanotic metastases did not show significant differences of SWI blooming artifacts (38
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:30793419
%R 10.1002/jmri.26692
%U https://inrepo02.dkfz.de/record/147217