TY  - JOUR
AU  - Schwarz, Daniel
AU  - Niederle, Thomas
AU  - Münch, Philipp
AU  - Hielscher, Thomas
AU  - Hassel, Jessica C
AU  - Schlemmer, Heinz-Peter
AU  - Platten, Michael
AU  - Winkler, Frank
AU  - Wick, Wolfgang
AU  - Heiland, Sabine
AU  - Delorme, Stefan
AU  - Bendszus, Martin
AU  - Bäumer, Philipp
AU  - Breckwoldt, Michael
TI  - Susceptibility-weighted imaging in malignant melanoma brain metastasis.
JO  - Journal of magnetic resonance imaging
VL  - 50
IS  - 4
SN  - 1522-2586
CY  - New York, NY
PB  - Wiley-Liss
M1  - DKFZ-2019-02343
SP  - 1251 - 1259
PY  - 2019
AB  - The value of cerebral susceptibility-weighted imaging (SWI) in malignant melanoma (MM) patients remains controversial and the effect of melanin on SWI is not well understood.To systematically analyze the spectrum of intracerebral findings in MM brain metastases (BM) on SWI and to determine the diagnostic value of SWI.Retrospective.In all, 100 patients with melanoma BM (69 having received radiotherapy [RT] and 31 RT-naïve) and a control group of 100 melanoma patients without BM were included. For detailed analysis of signal characteristics, 175 metastases were studied.Gradient echo SWI sequence at 1.5, 3.0, and 9.4 T.Signal characteristics from melanotic and amelanotic BMs on SWI with a focus on blooming artifacts were analyzed, as well as the presence and longitudinal dynamics of isolated SWI blooming artifacts in patients with and without BM.Chi-squared and Student's t-test were used for contingency table measures and group data of signal and clinical characteristics, respectively.Melanotic and amelanotic metastases did not show significant differences of SWI blooming artifacts (38
LB  - PUB:(DE-HGF)16
C6  - pmid:30793419
DO  - DOI:10.1002/jmri.26692
UR  - https://inrepo02.dkfz.de/record/147217
ER  -