000147238 001__ 147238 000147238 005__ 20240229112644.0 000147238 0247_ $$2doi$$a10.1001/jamaoncol.2019.2996 000147238 0247_ $$2pmid$$apmid:31560378 000147238 0247_ $$2pmc$$apmc:PMC6777271 000147238 0247_ $$2ISSN$$a2374-2437 000147238 0247_ $$2ISSN$$a2374-2445 000147238 0247_ $$2altmetric$$aaltmetric:67353795 000147238 037__ $$aDKFZ-2019-02364 000147238 041__ $$aeng 000147238 082__ $$a610 000147238 1001_ $$aGlobal Burden of Disease Cancer Collaboration$$b0$$eCollaboration Author 000147238 245__ $$aGlobal, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017: A Systematic Analysis for the Global Burden of Disease Study. 000147238 260__ $$aChicago, Ill.$$bAmerican Medical Association$$c2019 000147238 3367_ $$2DRIVER$$aarticle 000147238 3367_ $$2DataCite$$aOutput Types/Journal article 000147238 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1579530022_14013 000147238 3367_ $$2BibTeX$$aARTICLE 000147238 3367_ $$2ORCID$$aJOURNAL_ARTICLE 000147238 3367_ $$00$$2EndNote$$aJournal Article 000147238 500__ $$aJAMA Oncol. 2019;5(12):1749-1768 000147238 520__ $$aCancer and other noncommunicable diseases (NCDs) are now widely recognized as a threat to global development. The latest United Nations high-level meeting on NCDs reaffirmed this observation and also highlighted the slow progress in meeting the 2011 Political Declaration on the Prevention and Control of Noncommunicable Diseases and the third Sustainable Development Goal. Lack of situational analyses, priority setting, and budgeting have been identified as major obstacles in achieving these goals. All of these have in common that they require information on the local cancer epidemiology. The Global Burden of Disease (GBD) study is uniquely poised to provide these crucial data.To describe cancer burden for 29 cancer groups in 195 countries from 1990 through 2017 to provide data needed for cancer control planning.We used the GBD study estimation methods to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life-years (DALYs). Results are presented at the national level as well as by Socio-demographic Index (SDI), a composite indicator of income, educational attainment, and total fertility rate. We also analyzed the influence of the epidemiological vs the demographic transition on cancer incidence.In 2017, there were 24.5 million incident cancer cases worldwide (16.8 million without nonmelanoma skin cancer [NMSC]) and 9.6 million cancer deaths. The majority of cancer DALYs came from years of life lost (97%), and only 3% came from years lived with disability. The odds of developing cancer were the lowest in the low SDI quintile (1 in 7) and the highest in the high SDI quintile (1 in 2) for both sexes. In 2017, the most common incident cancers in men were NMSC (4.3 million incident cases); tracheal, bronchus, and lung (TBL) cancer (1.5 million incident cases); and prostate cancer (1.3 million incident cases). The most common causes of cancer deaths and DALYs for men were TBL cancer (1.3 million deaths and 28.4 million DALYs), liver cancer (572 000 deaths and 15.2 million DALYs), and stomach cancer (542 000 deaths and 12.2 million DALYs). For women in 2017, the most common incident cancers were NMSC (3.3 million incident cases), breast cancer (1.9 million incident cases), and colorectal cancer (819 000 incident cases). The leading causes of cancer deaths and DALYs for women were breast cancer (601 000 deaths and 17.4 million DALYs), TBL cancer (596 000 deaths and 12.6 million DALYs), and colorectal cancer (414 000 deaths and 8.3 million DALYs).The national epidemiological profiles of cancer burden in the GBD study show large heterogeneities, which are a reflection of different exposures to risk factors, economic settings, lifestyles, and access to care and screening. The GBD study can be used by policy makers and other stakeholders to develop and improve national and local cancer control in order to achieve the global targets and improve equity in cancer care. 000147238 536__ $$0G:(DE-HGF)POF3-313$$a313 - Cancer risk factors and prevention (POF3-313)$$cPOF3-313$$fPOF III$$x0 000147238 588__ $$aDataset connected to CrossRef, PubMed, 000147238 7001_ $$aFitzmaurice, Christina$$b1 000147238 7001_ $$aAbate, Degu$$b2 000147238 7001_ $$aAbbasi, Naghmeh$$b3 000147238 7001_ $$aAbbastabar, Hedayat$$b4 000147238 7001_ $$aAbd-Allah, Foad$$b5 000147238 7001_ $$aAbdel-Rahman, Omar$$b6 000147238 7001_ $$aAbdelalim, Ahmed$$b7 000147238 7001_ $$aAbdoli, Amir$$b8 000147238 7001_ $$aAbdollahpour, Ibrahim$$b9 000147238 7001_ $$aAbdulle, Abdishakur S M$$b10 000147238 7001_ $$aAbebe, Nebiyu Dereje$$b11 000147238 7001_ $$aAbraha, Haftom Niguse$$b12 000147238 7001_ $$aAbu-Raddad, Laith Jamal$$b13 000147238 7001_ $$aAbualhasan, Ahmed$$b14 000147238 7001_ $$aAdedeji, Isaac 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Tesfaye Yitna$$b129 000147238 7001_ $$aChido-Amajuoyi, Onyema Greg$$b130 000147238 7001_ $$aChimed-Ochir, Odgerel$$b131 000147238 7001_ $$aChoi, Jee-Young J$$b132 000147238 7001_ $$aChristopher, Devasahayam J$$b133 000147238 7001_ $$aChu, Dinh-Toi$$b134 000147238 7001_ $$aConstantin, Maria-Magdalena$$b135 000147238 7001_ $$aCosta, Vera M$$b136 000147238 7001_ $$aCrocetti, Emanuele$$b137 000147238 7001_ $$aCrowe, Christopher Stephen$$b138 000147238 7001_ $$aCurado, Maria Paula$$b139 000147238 7001_ $$aDahlawi, Saad M A$$b140 000147238 7001_ $$aDamiani, Giovanni$$b141 000147238 7001_ $$aDarwish, Amira Hamed$$b142 000147238 7001_ $$aDaryani, Ahmad$$b143 000147238 7001_ $$adas Neves, José$$b144 000147238 7001_ $$aDemeke, Feleke Mekonnen$$b145 000147238 7001_ $$aDemis, Asmamaw Bizuneh$$b146 000147238 7001_ $$aDemissie, Birhanu Wondimeneh$$b147 000147238 7001_ $$aDemoz, Gebre Teklemariam$$b148 000147238 7001_ $$aDenova-Gutiérrez, Edgar$$b149 000147238 7001_ $$aDerakhshani, Afshin$$b150 000147238 7001_ $$aDeribe, Kalkidan Solomon$$b151 000147238 7001_ $$aDesai, Rupak$$b152 000147238 7001_ $$aDesalegn, Beruk Berhanu$$b153 000147238 7001_ $$aDesta, Melaku$$b154 000147238 7001_ $$aDey, Subhojit$$b155 000147238 7001_ $$aDharmaratne, Samath Dhamminda$$b156 000147238 7001_ $$aDhimal, Meghnath$$b157 000147238 7001_ $$aDiaz, Daniel$$b158 000147238 7001_ $$aDinberu, Mesfin Tadese Tadese$$b159 000147238 7001_ $$aDjalalinia, Shirin$$b160 000147238 7001_ $$aDoku, David Teye$$b161 000147238 7001_ $$aDrake, Thomas M$$b162 000147238 7001_ $$aDubey, Manisha$$b163 000147238 7001_ $$aDubljanin, Eleonora$$b164 000147238 7001_ $$aDuken, Eyasu Ejeta$$b165 000147238 7001_ $$aEbrahimi, Hedyeh$$b166 000147238 7001_ $$aEffiong, Andem$$b167 000147238 7001_ $$aEftekhari, Aziz$$b168 000147238 7001_ $$aEl Sayed, Iman$$b169 000147238 7001_ $$aZaki, Maysaa El Sayed$$b170 000147238 7001_ $$aEl-Jaafary, Shaimaa I$$b171 000147238 7001_ $$aEl-Khatib, Ziad$$b172 000147238 7001_ $$aElemineh, Demelash Abewa$$b173 000147238 7001_ $$aElkout, Hajer$$b174 000147238 7001_ $$aEllenbogen, Richard G$$b175 000147238 7001_ $$aElsharkawy, Aisha$$b176 000147238 7001_ $$aEmamian, Mohammad Hassan$$b177 000147238 7001_ $$aEndalew, Daniel Adane$$b178 000147238 7001_ $$aEndries, Aman Yesuf$$b179 000147238 7001_ $$aEshrati, Babak$$b180 000147238 7001_ $$aFadhil, Ibtihal$$b181 000147238 7001_ $$aFallah, Vahid$$b182 000147238 7001_ $$aFaramarzi, Mahbobeh$$b183 000147238 7001_ $$aFarhangi, Mahdieh Abbasalizad$$b184 000147238 7001_ $$aFarioli, Andrea$$b185 000147238 7001_ $$aFarzadfar, Farshad$$b186 000147238 7001_ $$aFentahun, Netsanet$$b187 000147238 7001_ $$aFernandes, Eduarda$$b188 000147238 7001_ $$aFeyissa, Garumma Tolu$$b189 000147238 7001_ $$aFilip, Irina$$b190 000147238 7001_ $$aFischer, Florian$$b191 000147238 7001_ $$aFisher, James L$$b192 000147238 7001_ $$aForce, Lisa M$$b193 000147238 7001_ $$aForoutan, Masoud$$b194 000147238 7001_ $$aFreitas, Marisa$$b195 000147238 7001_ $$aFukumoto, Takeshi$$b196 000147238 7001_ $$aFutran, Neal D$$b197 000147238 7001_ $$aGallus, Silvano$$b198 000147238 7001_ $$aGankpe, Fortune Gbetoho$$b199 000147238 7001_ $$aGayesa, Reta Tsegaye$$b200 000147238 7001_ $$aGebrehiwot, Tsegaye Tewelde$$b201 000147238 7001_ $$aGebremeskel, Gebreamlak Gebremedhn$$b202 000147238 7001_ $$aGedefaw, Getnet Azeze$$b203 000147238 7001_ $$aGelaw, Belayneh K$$b204 000147238 7001_ $$aGeta, Birhanu$$b205 000147238 7001_ $$aGetachew, Sefonias$$b206 000147238 7001_ $$aGezae, Kebede Embaye$$b207 000147238 7001_ $$aGhafourifard, Mansour$$b208 000147238 7001_ $$aGhajar, Alireza$$b209 000147238 7001_ $$aGhashghaee, Ahmad$$b210 000147238 7001_ $$aGholamian, Asadollah$$b211 000147238 7001_ $$aGill, Paramjit Singh$$b212 000147238 7001_ $$aGinindza, Themba T G$$b213 000147238 7001_ $$aGirmay, Alem$$b214 000147238 7001_ $$aGizaw, Muluken$$b215 000147238 7001_ $$aGomez, Ricardo Santiago$$b216 000147238 7001_ $$aGopalani, Sameer Vali$$b217 000147238 7001_ $$aGorini, Giuseppe$$b218 000147238 7001_ $$aGoulart, Bárbara Niegia Garcia$$b219 000147238 7001_ $$aGrada, Ayman$$b220 000147238 7001_ $$aRibeiro Guerra, Maximiliano$$b221 000147238 7001_ $$aGuimaraes, Andre Luiz Sena$$b222 000147238 7001_ $$aGupta, Prakash C$$b223 000147238 7001_ $$aGupta, Rahul$$b224 000147238 7001_ $$aHadkhale, Kishor$$b225 000147238 7001_ $$aHaj-Mirzaian, Arvin$$b226 000147238 7001_ $$aHaj-Mirzaian, Arya$$b227 000147238 7001_ $$aHamadeh, Randah R$$b228 000147238 7001_ $$aHamidi, Samer$$b229 000147238 7001_ $$aHanfore, Lolemo Kelbiso$$b230 000147238 7001_ $$aHaro, Josep Maria$$b231 000147238 7001_ $$aHasankhani, Milad$$b232 000147238 7001_ $$aHasanzadeh, Amir$$b233 000147238 7001_ $$aHassen, Hamid Yimam$$b234 000147238 7001_ $$aHay, Roderick J$$b235 000147238 7001_ $$aHay, Simon I$$b236 000147238 7001_ $$aHenok, Andualem$$b237 000147238 7001_ $$aHenry, Nathaniel J$$b238 000147238 7001_ $$aHerteliu, Claudiu$$b239 000147238 7001_ $$aHidru, Hagos D$$b240 000147238 7001_ $$aHoang, Chi Linh$$b241 000147238 7001_ $$aHole, Michael K$$b242 000147238 7001_ $$aHoogar, Praveen$$b243 000147238 7001_ $$aHorita, Nobuyuki$$b244 000147238 7001_ $$aHosgood, H Dean$$b245 000147238 7001_ $$aHosseini, Mostafa$$b246 000147238 7001_ $$aHosseinzadeh, Mehdi$$b247 000147238 7001_ $$aHostiuc, Mihaela$$b248 000147238 7001_ $$aHostiuc, Sorin$$b249 000147238 7001_ $$aHouseh, Mowafa$$b250 000147238 7001_ $$aHussen, Mohammedaman Mama$$b251 000147238 7001_ $$aIleanu, Bogdan$$b252 000147238 7001_ $$aIlic, Milena D$$b253 000147238 7001_ $$aInnos, Kaire$$b254 000147238 7001_ $$aIrvani, Seyed Sina Naghibi$$b255 000147238 7001_ $$aIseh, Kufre Robert$$b256 000147238 7001_ $$aIslam, Sheikh Mohammed Shariful$$b257 000147238 7001_ $$aIslami, Farhad$$b258 000147238 7001_ $$aJafari Balalami, Nader$$b259 000147238 7001_ $$aJafarinia, Morteza$$b260 000147238 7001_ $$aJahangiry, Leila$$b261 000147238 7001_ $$aJahani, Mohammad Ali$$b262 000147238 7001_ $$aJahanmehr, Nader$$b263 000147238 7001_ 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