% IMPORTANT: The following is UTF-8 encoded. This means that in the presence % of non-ASCII characters, it will not work with BibTeX 0.99 or older. % Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or % “biber”. @ARTICLE{Collaboration:147697, author = {C. Taddei and R. Jackson and B. Zhou and H. Bixby and G. Danaei and M. Di Cesare and K. Kuulasmaa and K. Hajifathalian and J. Bentham and J. E. Bennett and W. Aekplakorn and R. Cifkova and J. Dallongeville and D. DeBacquer and S. Giampaoli and V. Gudnason and Y.-H. Khang and T. Laatikainen and J. Mann and P. Marques-Vidal and G. Mensah and M. Müller-Nurasyid and T. Ninomiya and J. Petkeviciene and F. Rodríguez-Artalejo and J. Servais and S. Söderberg and B. Stavreski and T. Wilsgaard and T. Zdrojewski and D. Zhao and G. Stevens and S. Savin and M. Cowan and L. Riley and M. Ezzati and R. Adams and W. Aekplakorn and W. Ahrens and P. Amouyel and A. Amuzu and S. Anderssen and I. Ariansen and D. Arveiler and T. Aspelund and J. Auvinen and M. Avdicová and M. Banach and P. Bandosz and J. Banegas and C. Barbagallo and I. Bata and L. Baur and R. Beaglehole and J. Bennett and G. Bernotiene and Y. Bi and A. Bienek and C. Björkelund and S. Bo and B. Boehm and M. Bonaccio and V. Bongard and R. Borchini and H. Borghs and J. Breckenkamp and H. Brenner$^*$ and G. Bruno and M. Busch and A. CabreradeLeón and V. Capuano and F. Casanueva and J.-P. Casas and C. Caserta and L. Censi and F. Chen and S. Chen and M.-D. Chirlaque and B. Cho and Y. Cho and J. Chudek and R. Cifkova and F. Claessens and J. Clarke and E. Clays and C. Cooper and S. Costanzo and D. Cottel and C. Cowell and A. Crujeiras and L. Cui and G. D'Arrigo and J. Dallongeville and L. Dauchet and G. De Backer and D. De Bacquer and G. de Gaetano and S. De Henauw and D. De Smedt and E. Dennison and V. Deschamps and A. DiCastelnuovo and A. Dobson and C. Donfrancesco and A. Döring and W. Drygas and Y. Du and E. Dziankowska-Zaborszczyk and R. Eggertsen and U. Ekelund and R. Elosua and J. Eriksson and A. Evans and D. Faeh and F. Felix-Redondo and D. Fernández-Bergés and M. Ferrari and J. Ferrieres and J. Finn and A.-S. Forslund and M. Forsner and G. Frontera and Y. Fujita and Z. Gaciong and F. Galvano and J. Gao and M. Garcia-de-la-Hera and S. Garnett and J.-M. Gaspoz and M. Gasull and L. Gates and S. Giampaoli and F. Gianfagna and T. Gill and J. Giovannelli and D. Goltzman and M. GonzalezGross and F. Gottrand and S. Graff-Iversen and D. Grafnetter and R. Gregor and T. Grodzicki and G. Grosso and G. Gruden and D. Gu and P. Guallar-Castillón and E. Gudmundsson and V. Gudnason and I. Guessous and J. Gunnlaugsdottir and F. Gutzwiller and R. Hardy and J. Hata and T. Haugsgjerd and A. Hayes and J. He and Y. He and S. Herrala and I. TapaniHihtaniemi and M. Hobbs and W. Hopman and J. MaríaHuerta and I. Huybrechts and L. Iacoviello and A. Iannone and N. Ikeda and M. Iwasaki and R. Jackson and K. Jamrozik and I. Janszky and M.-R. Jarvelin and G. Jasienska and G. Jennings and S.-L. Jeong and C. QiangJiang and M. Joffres and J. Jokelainen and J. Jonas and J. Jóźwiak and E. Kajantie and J. Kauhanen and U. Keil and S. Keinänen-Kiukaanniemi and M. Kersting and Y.-H. Khang and U. Kiechl-Kohlendorfer and S. Kiechl and J. Kim and Y.-Y. Kim and J. Klumbiene and M. Knoflach and S. Ko and E. Kolle and R. Korpelainen and S. Koskinen and K. Kouda and W. Kratzer and S. Kriemler and S. Krokstad and U. Kujala and P. Kurjata and K. Kuulasmaa and T. Laatikainen and T. HingLam and V. Lanska and G. Lappas and L. Laugsand and J. Lee and T. Lehtimäki and Y. Li and C. Lilly and X. Lin and L. Lind and L. Lissner and J. Liu and E. Lopez-Garcia and R. Lorbeer and J. EugenioLozano and D. Luksiene and A. Lundqvist and R. Lundqvist and P. Lytsy and G. Ma and S. Machi and S. Maggi and D. Magliano and J. Mann and E. Manzato and P. Marques-Vidal and E. Mathiesen and S. McLachlan and R. McLean and B. Scott and A. Meirhaeghe and P. Metcalf and J. Mi and J. Miller and L. Moreno and S. Morin and M. Mossakowska and M. Muiesan and M. Müller-Nurasyid and J. Mursu and H. Nakamura and J. Námešná and E. MariaNavarrete-Muñoz and W. Neal and I. Nenko and T. Niiranen and G. Ning and T. Ninomiya and M. Noale and S. Norie and D. Noto and T. O'Neill and D. O'Reilly and K. Oh and Ö. Olafsson and F. MichelPaccaud and A. Pajak and L. Palmieri and F. Panza and W. Parnell and M. Peltonen and A. Peters and A. Petersmann and J. Petkeviciene and I. Pigeot and L. Pilotto and A. Piwonska and P. Plans-Rubió and M. Porta and J. Price and J. Puder and S. Puhakka and R. Radisauskas and O. Raitakari and R. Ramos and J. Redon and F. Rigo and F. Rodríguez-Artalejo and M. Rodriguez-Perez and D. Romaguera and K. Ronkainen and A. Rosengren and J. G. R. Roy and J.-B. Ruidavets and M. Rutkowski and B. Salanave and D. Salmerón and V. Salomaa and J. Salonen and M. Salvetti and S. Sans and J. Saramies and K.-U. Saum and C. Scheidt-Nave and A. Schienkiewitz and S. Schipf and C. Schmidt and B. Schöttker$^*$ and S. Sebert and A. Sen and J. Servais and J. Shaw and K. Shibuya and D. WookShin and R. Shiri and J. Simons and L. Simons and M. Sjöström and J. Slowikowska-Hilczer and P. Slusarczyk and S. Söderberg and V. Solfrizzi and E. Sonestedt and A. Soumare and J. Staessen and M. Stathopoulou and B. Stavreski and J. Steene-Johannessen and P. Stehle and J. Stieber and D. Stöckl and J. Stokwiszewski and J. Sundström and P. Suriyawongpaisal and A. Tamosiunas and E. JooTan and A. Taylor and G. Tell and L. Thijs and H. Tolonen and R. Topór-Madry and M. JoséTormo and M. Torrent and S. Tsugane and T.-P. Tuomainen and J. Tuomilehto and C. Tzourio and H. M. T. Uusitalo and K. VanHerck and D. Vanderschueren and D. Vanuzzo and L. Vatten and T. Vega and G. Veronesi and J. Vioque and J. Virtanen and S. Visvikis-Siest and P. Vollenweider and S. Voutilainen and M. Vrijheid and A. Wagner and A. Wagner and M.-D. Wang and Q. Wang and Y. XingWang and S. Goya Wannamethee and W. Wei and P. Whincup and A. Wiecek and J. Willeit and P. Willeit and T. Wilsgaard and B. Wojtyniak and A. Wong and M. Woodward and A. GiwercmanWu and F. Wu and S. Wu and H. Xu and L. Xu and W. Yan and X. Yang and X. Ye and A. Yoshihara and S. Zambon and T. Zdrojewski and D. Zhao and W. Zhao}, collaboration = {NCD Risk {Factor Collaboration}}, title = {{N}ational trends in total cholesterol obscure heterogeneous changes in {HDL} and non-{HDL} cholesterol and total-to-{HDL} cholesterol ratio: a pooled analysis of 458 population-based studies in {A}sian and {W}estern countries.}, journal = {International journal of epidemiology}, volume = {49}, number = {1}, issn = {1464-3685}, address = {Oxford}, publisher = {Oxford Univ. Press}, reportid = {DKFZ-2019-02679}, pages = {173-192}, year = {2020}, note = {2020 Feb 1;49(1):173-192}, abstract = {Although high-density lipoprotein (HDL) and non-HDL cholesterol have opposite associations with coronary heart disease, multi-country reports of lipid trends only use total cholesterol (TC). Our aim was to compare trends in total, HDL and non-HDL cholesterol and the total-to-HDL cholesterol ratio in Asian and Western countries.We pooled 458 population-based studies with 82.1 million participants in 23 Asian and Western countries. We estimated changes in mean total, HDL and non-HDL cholesterol and mean total-to-HDL cholesterol ratio by country, sex and age group.Since ∼1980, mean TC increased in Asian countries. In Japan and South Korea, the TC rise was due to rising HDL cholesterol, which increased by up to 0.17 mmol/L per decade in Japanese women; in China, it was due to rising non-HDL cholesterol. TC declined in Western countries, except in Polish men. The decline was largest in Finland and Norway, at ∼0.4 mmol/L per decade. The decline in TC in most Western countries was the net effect of an increase in HDL cholesterol and a decline in non-HDL cholesterol, with the HDL cholesterol increase largest in New Zealand and Switzerland. Mean total-to-HDL cholesterol ratio declined in Japan, South Korea and most Western countries, by as much as ∼0.7 per decade in Swiss men (equivalent to $∼26\%$ decline in coronary heart disease risk per decade). The ratio increased in China.HDL cholesterol has risen and the total-to-HDL cholesterol ratio has declined in many Western countries, Japan and South Korea, with only a weak correlation with changes in TC or non-HDL cholesterol.}, cin = {C070 / C120}, ddc = {610}, cid = {I:(DE-He78)C070-20160331 / I:(DE-He78)C120-20160331}, pnm = {313 - Cancer risk factors and prevention (POF3-313)}, pid = {G:(DE-HGF)POF3-313}, typ = {PUB:(DE-HGF)16}, pubmed = {pmid:31321439}, doi = {10.1093/ije/dyz099}, url = {https://inrepo02.dkfz.de/record/147697}, }