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@ARTICLE{dErrico:148295,
      author       = {M. d'Errico$^*$ and E. Alwers$^*$ and Y. Zhang$^*$ and D.
                      Edelmann$^*$ and H. Brenner$^*$ and M. Hoffmeister$^*$},
      title        = {{I}dentification of prognostic {DNA} methylation biomarkers
                      in patients with gastrointestinal adenocarcinomas: {A}
                      systematic review of epigenome-wide studies.},
      journal      = {Cancer treatment reviews},
      volume       = {82},
      issn         = {0305-7372},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier},
      reportid     = {DKFZ-2019-02859},
      pages        = {101933},
      year         = {2020},
      note         = {2020 Jan;82:101933#EA:C070#LA:C070#},
      abstract     = {This systematic review aims to summarize epigenome-wide
                      studies on aberrant DNA methylation and its association with
                      survival in patients with gastrointestinal adenocarcinoma.
                      The 15 studies identified showed a large variety of
                      methodological approaches for the identification of
                      prognostic epigenetic markers from genome-wide methylation
                      analyses. None of the findings were reported by more than
                      one study in this systematic review. Further validation
                      studies, a better reporting of methods and results are
                      needed, as well as a clearer definition of investigated
                      outcomes. At present, no conclusions can be drawn on the
                      clinical relevance of the reported epigenetic markers.},
      subtyp        = {Review Article},
      cin          = {C070 / C060 / C120 / HD01},
      ddc          = {610},
      cid          = {I:(DE-He78)C070-20160331 / I:(DE-He78)C060-20160331 /
                      I:(DE-He78)C120-20160331 / I:(DE-He78)HD01-20160331},
      pnm          = {313 - Cancer risk factors and prevention (POF3-313)},
      pid          = {G:(DE-HGF)POF3-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:31785412},
      doi          = {10.1016/j.ctrv.2019.101933},
      url          = {https://inrepo02.dkfz.de/record/148295},
}