TY - JOUR AU - Karavasiloglou, Nena AU - Hüsing, Anika AU - Masala, Giovanna AU - van Gils, Carla H AU - Turzanski Fortner, Renée AU - Chang-Claude, Jenny AU - Huybrechts, Inge AU - Weiderpass, Elisabete AU - Gunter, Marc AU - Arveux, Patrick AU - Fournier, Agnès AU - Kvaskoff, Marina AU - Tjønneland, Anne AU - Kyrø, Cecilie AU - Dahm, Christina C AU - Vistisen, Helene Tilma AU - Bakker, Marije F AU - Sánchez, Maria-Jose AU - Chirlaque López, María Dolores AU - Santiuste, Carmen AU - Ardanaz, Eva AU - Menéndez, Virginia AU - Agudo, Antonio AU - Trichopoulou, Antonia AU - Karakatsani, Anna AU - La Vecchia, Carlo AU - Peppa, Eleni AU - Palli, Domenico AU - Agnoli, Claudia AU - Panico, Salvatore AU - Tumino, Rosario AU - Sacerdote, Carlotta AU - Butt, Salma Tunå AU - Borgquist, Signe AU - Skeie, Guri AU - Schulze, Matthias AU - Key, Timothy AU - Khaw, Kay-Tee AU - Tsilidis, Kostantinos K AU - Ellingjord-Dale, Merete AU - Riboli, Elio AU - Kaaks, Rudolf AU - Dossus, Laure AU - Rohrmann, Sabine AU - Kühn, Tilman TI - Adherence to the World Cancer Research Fund/American Institute for Cancer Research cancer prevention recommendations and risk of in situ breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. JO - BMC medicine VL - 17 IS - 1 SN - 1741-7015 CY - Heidelberg [u.a.] PB - Springer M1 - DKFZ-2019-02881 SP - 221 PY - 2019 N1 - EA: C020LA: C020 AB - Even though in situ breast cancer (BCIS) accounts for a large proportion of the breast cancers diagnosed, few studies have investigated potential risk factors for BCIS. Their results suggest that some established risk factors for invasive breast cancer have a similar impact on BCIS risk, but large population-based studies on lifestyle factors and BCIS risk are lacking. Thus, we investigated the association between lifestyle and BCIS risk within the European Prospective Investigation into Cancer and Nutrition cohort.Lifestyle was operationalized by a score reflecting the adherence to the World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) cancer prevention recommendations. The recommendations utilized in these analyses were the ones pertinent to healthy body weight, physical activity, consumption of plant-based foods, energy-dense foods, red and processed meat, and sugary drinks and alcohol, as well as the recommendation on breastfeeding. Cox proportional hazards regression was used to assess the association between lifestyle score and BCIS risk. The results were presented as hazard ratios (HR) and corresponding 95 LB - PUB:(DE-HGF)16 C6 - pmid:31787099 DO - DOI:10.1186/s12916-019-1444-0 UR - https://inrepo02.dkfz.de/record/148323 ER -