001     148379
005     20240229123032.0
024 7 _ |a 10.1136/ijgc-2019-000585
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024 7 _ |a pmid:31796532
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024 7 _ |a 1048-891X
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024 7 _ |a 1525-1438
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024 7 _ |a altmetric:73668297
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037 _ _ |a DKFZ-2019-02935
041 _ _ |a eng
082 _ _ |a 610
100 1 _ |a Maurer, Tabea
|b 0
245 _ _ |a An exercise and nutrition intervention for ovarian cancer patients during and after first-line chemotherapy (BENITA study): a randomized controlled pilot trial.
260 _ _ |a Baltimore,MD [u.a.]
|c 2020
|b Lippincott, Williams & Wilkins
336 7 _ |a article
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336 7 _ |a Journal Article
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336 7 _ |a ARTICLE
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336 7 _ |a Journal Article
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500 _ _ |a #LA:C020#2020 Apr;30(4):541-545
520 _ _ |a Data on the treatment-supporting effect of modifiable lifestyle factors such as nutrition and physical activity on survival or quality of life (QoL) are scarce in patients with ovarian cancer. Despite a strong rationale for evaluating the effect of a multimodal intervention and multiple studies targeting other cancer sites, randomized controlled trials (RCTs) on the effects of a combined nutrition and exercise intervention on survival and QoL in ovarian cancer patients are rare. No study has investigated the impact of an early intervention during first-line chemotherapy.To evaluate the study design, feasibility, safety, and acceptance of combined nutrition and exercise in patients diagnosed with ovarian cancer during and after first-line chemotherapy.Physical exercise and a cancer-specific nutrition intervention after ovarian cancer diagnosis is feasible, accepted, and safe for patients receiving first-line chemotherapy.A 1:1 RCT with an intervention group and a control group. The intervention group receives an exercise and nutrition program whereas the control group continues to follow the usual care.Inclusion: women ≥18 years of age; women diagnosed with ovarian cancer, tubal cancer, or peritoneal cancer and primary or interval debulking surgery. Exclusion: Eastern Cooperative Oncology Group (ECOG) status of 2 or worse.Recruitment rate, completion rate, side effects, and adherence.n=30 patients (15 per arm) will be recruited.Accrual completion is planned for the end of 2019. Results will be presented in the months following study completion 1 year after recruitment has been finalised.The pilot phase was approved by the ethics committee of the Medical Faculty of Hamburg on December 13, 2017 (PV5456). The study was registered on September 9, 2018 at the German Study Registry for Clinical Studies (DRKS00013231).
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700 1 _ |a von Grundherr, Julia
|b 1
700 1 _ |a Patra, Stefan
|b 2
700 1 _ |a Jäger, Anna
|b 3
700 1 _ |a Becher, Heiko
|b 4
700 1 _ |a Schmalfeld, Barbara
|b 5
700 1 _ |a Zyriax, Birgit-Christiane
|b 6
700 1 _ |a Chang-Claude, Jenny
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773 _ _ |a 10.1136/ijgc-2019-000585
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|0 PERI:(DE-600)2009072-9
|n 4
|p 541-545
|t International journal of gynecological cancer
|v 30
|y 2020
|x 1525-1438
909 C O |p VDB
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910 1 _ |a Deutsches Krebsforschungszentrum
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914 1 _ |y 2020
915 _ _ |a Nationallizenz
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